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Latest Abstracts Imported from Pubmed.gov, Rated & Indexed

Plumbagin ameliorates renal fibrosis by suppressing epithelial-mesenchymal transition.

Article Published Date : Feb 28, 2025
Study Type : Animal Study
Additional Links
Substances : Plumbagin : CK(36) : AC(23)
Diseases : Kidney Fibrosis : CK(265) : AC(149)
Pharmacological Actions : Anti-Fibrotic : CK(2355) : AC(1115), Renoprotective : CK(4776) : AC(2072)

Plumbagin induces apoptosis in diffuse large B-cell lymphoma.

Article Published Date : Dec 31, 2024
Study Type : In Vitro Study
Additional Links
Substances : Plumbagin : CK(8) : AC(16)
Diseases : Lymphoma: B-Cell : CK(72) : AC(44)
Pharmacological Actions : Antiproliferative : CK(10364) : AC(7758), Apoptotic : CK(9850) : AC(7598)

Plumbagin inhibits cadmium-induced IL-6/STAT3 signaling in a triple-negative breast cancer cells.

Article Published Date : Jan 31, 2025
Study Type : In Vitro Study
Additional Links
Substances : Plumbagin : CK(8) : AC(16)
Diseases : Breast Cancer: Triple Negative : CK(1000) : AC(684)
Pharmacological Actions : Antiproliferative : CK(10364) : AC(7758), Interleukin-6 Downregulation : CK(9804) : AC(3793)

Antibiofilm activity of Plumbagin against Staphylococcus aureus.

Article Published Date : Mar 06, 2025
Study Type : In Vitro Study
Additional Links
Substances : Plumbagin : CK(8) : AC(16)
Diseases : Staphylococcus aureus infection : CK(796) : AC(594)
Pharmacological Actions : Anti-Bacterial Agents : CK(4337) : AC(2055)
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

Plumbagin exhibits antifungal efficacy against C. auris.

Article Published Date : Feb 28, 2025

In silico analysis of plumbagin's interaction with caspase 9.

Article Published Date : Apr 10, 2025
Study Type : In Vitro Study
Additional Links
Substances : Plumbagin : CK(8) : AC(16)
Diseases : Non-Small-Cell Lung Carcinoma : CK(91) : AC(67)
Pharmacological Actions : Apoptotic : CK(9850) : AC(7598)

Plumbagin as a potential therapeutic agent for scopolamine-induced Alzheimer's disease.

Article Published Date : Jul 14, 2025
Study Type : Animal Study
Additional Links
Substances : Plumbagin : CK(8) : AC(16)
Diseases : Alzheimer's Disease : CK(5546) : AC(2306), Oxidative Stress : CK(15818) : AC(6147)
Pharmacological Actions : Neuroprotective Agents : CK(21218) : AC(8383)

Synergistic inhibition of colon cancer cell proliferation via p53, Bax, and Bcl-2 modulation by curcumin and plumbagin combination.

Article Published Date : May 12, 2025
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(8599) : AC(3784), Plumbagin : CK(8) : AC(16)
Diseases : Colon Cancer : CK(1943) : AC(1216)
Pharmacological Actions : Antiproliferative : CK(10364) : AC(7757)

Plumbagin alleviates social behavior deficits in a valproic acid model of autism.

Article Published Date : May 19, 2025
Study Type : Animal Study
Additional Links
Substances : Plumbagin : CK(8) : AC(15)
Diseases : Autism Spectrum Disorders : CK(3748) : AC(583), Oxidative Stress : CK(15816) : AC(6146)
Pharmacological Actions : Antioxidants : CK(36280) : AC(15170), Brain-derived neurotrophic factor modulator : CK(781) : AC(295), Heme oxygenase-1 up-regulation : CK(1415) : AC(819), Nrf2 activation : CK(3310) : AC(1879), SIRT1 Activator : CK(400) : AC(201), Transforming growth factor beta (TGF-β) upregulation : CK(198) : AC(78)

Plumbagin ameliorates ferroptosis of ovarian granulosa cells in polycystic ovary syndrome.

Article Published Date : Jun 01, 2025
Study Type : In Vitro Study
Additional Links
Substances : Plumbagin : CK(8) : AC(6)
Diseases : Lipid Peroxidation : CK(2113) : AC(835), Polycystic Ovary Syndrome : CK(2167) : AC(345)
Pharmacological Actions : Antioxidants : CK(36280) : AC(15170)

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