Research Abstracts Database

Animal Study

Curcumol Alleviates Ferroptosis in Metabolic-Associated Fatty Liver Disease by Inhibiting EGFR-Endoplasmic Reticulum Stress Axis.

Sep 11, 2026 Wang Z, Fu Y, Zheng W, Zeng X, Xu Z, Chen J, Liu X, Qin H

Phytotherapy research : PTR

Curcumol

Fatty Liver

Hepatoprotective

View abstract

Animal Study

Anti-Inflammatory Effects of Bisacurone Isolated from Curcuma longa (Ryudai Gold): An In Vivo and In Silico Study.

Sep 10, 2026 Anjum M, Hossain MA, Akter J, Miyamoto A, Islam MZ

Molecules (Basel, Switzerland)

Turmeric

Inflammation

Anti-Inflammatory Agents

View abstract

Animal Study

Activating PXR by Curcumol Ameliorates DSS-Induced Ulcerative Colitis via Transcriptional Repression of STING Signaling.

Sep 10, 2026 Xie W, Yang T, Mo F, Meng W, Xu L, Liang J, Liu C, Zhong Y

Journal of agricultural and food chemistry

Curcumol

Ulcerative Colitis

Anti-Inflammatory Agents, Gastrointestinal Agents

View abstract

Animal Study

Curcumol targets the ATG4B-PKM2-lactate signaling axis to reverse EMT and inhibit colorectal cancer liver metastasis.

Sep 10, 2026 Wang G, Yue Z, Zhou W, Peng C, Bi T, Tan X, He W, Zhang Y, Deng Z, Zhang D, Yuan W, Bian Y, Yin G, Zhu L, Tang D

Phytomedicine : international journal of phytotherapy and phytopharmacology

Curcumol

Colorectal Cancer

Anti-metastatic

View abstract

In Vitro Study

Curcumol Induces G1 Phase Arrest in SK-Hep-1 Cells by Targeting SKP2-Mediated p27 Degradation.

Sep 10, 2026 Yang Y, Zhang R, Dou T, Liu Z, Ai R, Zhao Y, Cui Z, Chen X, Wang J

Molecules (Basel, Switzerland)

Curcumol

Liver Cancer

Antiproliferative, Cell cycle arrest, Cyclin D1 Down-Regulation

View abstract

Animal Study

Curcumol Ameliorates Diabetic Nephropathy by Inhibiting Podocyte Ferroptosis Through the xCT/GPX4 Pathway.

Sep 10, 2026 Ji Y, Wu Y, Tang J, Li Y, Guo X, Zhang J, Huang W, Liu Y, Liu Z, Liu WJ

Journal of diabetes research

Curcumol

Diabetic Nephropathy

Renoprotective

View abstract

Animal Study

Curcumol alleviates acute pancreatitis by inhibiting RIPK1/RIPK3/MLKL pathway-mediated necroptosis: integrated bioinformatics, network pharmacology, molecular docking and dynamics simulations, and experimental validation.

Sep 10, 2026 Li X, Hu Q, Chen J, Yang K, Ning F, Zeng X, Qin H

International immunopharmacology

Curcumol

Pancreatitis

Pancreato Protective Agents

View abstract

Animal Study

Curcumol Inhibits the Invasion and Migration of Breast Cancer via miR-206/NCL/ERα36.

Sep 10, 2026 Li X, Tian M, Zhou L, Ding H, Zhang R, Chen X, Wang J

Phytotherapy research : PTR

Curcumol

Breast Cancer

Anti-metastatic

View abstract

Animal Study

Micellar curcumol reprograms tumor-associated macrophages and reverses PARP inhibitor resistance in recurrent ovarian cancer.

Sep 10, 2026 Liu Q, Tang Q, Ye W, Chen B, Zhong Y, Song Y, Wang S, Zhou K, Jiang X, Wang J

Phytomedicine : international journal of phytotherapy and phytopharmacology

Curcumol

Ovarian Cancer

Anti-Inflammatory Agents, Immunomodulatory, Chemotherapeutic, Chemosensitizer, Interleukin-1 beta downregulation, Interleukin-18 down-regulation

View abstract

Animal Study

Curcumol Inhibits the Laminin-Facilitated Malignant Progression in Small-Cell Lung Cancer via Disrupting Laminin-Integrin β1 Interaction.

Sep 10, 2026 Qin J, Huang H, Xu M, Zhu L, Liu H, Qian X

Phytotherapy research : PTR

Curcumol

Non-Small-Cell Lung Carcinoma

Antiproliferative

View abstract

Animal Study

Curcumol Alleviates Obesity-Related Insulin Resistance and Inflammation in Skeletal Muscle via the SRC/PI3K/AKT Axis.

Sep 10, 2026 Fu Y, Zeng X, Zhou B, Wang J, Qin H

Nutrients

Curcumol

Inflammation, Insulin Resistance, Obesity

Anti-Inflammatory Agents, NF-kappaB Inhibitor, Insulin Sensitizers

View abstract

Human Study

Effects of Curcuma longa extract on cognitive function in healthy participants with subtle cognitive weaknesses within the normal range: a randomized, double-blind, placebo-controlled trial.

Sep 10, 2026 Saji R, Uchio R, Asada K, Okuda-Hanafusa C, Tokaji A, Muroyama K, Murosaki S, Yamamoto Y, Hirose Y, Kawasaki K

Frontiers in nutrition

Turmeric

Cognitive Decline/Dysfunction

Neuroprotective Agents

View abstract

Review

The Use of Curcumin to Target Oxidative Stress and Inflammation in Type 2 Diabetes Mellitus and Its Complications: Molecular Mechanisms and Therapeutic Perspectives.

Sep 10, 2026 Zhang J, Shu Q, Tang Y, Liu H, Zhang C, Chen X, Li S

Antioxidants (Basel, Switzerland)

Curcumin

Diabetes Mellitus: Type 2, Advanced Glycation End products (AGE)

Anti-Inflammatory Agents, Antioxidants, Gastrointestinal Agents, NF-kappaB Inhibitor, Insulin Sensitizers, Anti-Glycation Agents

View abstract

Animal Study

Curcumin and nanocurcumin attenuate ethanol-induced cognitive and oxidative impairments in male rats.

Sep 10, 2026 Ghobadi MJ, Valizadegan F, Hajizadeh Moghaddam A, Khanjani Jelodar S, Ahmadi Kholardi I, Babanezhad H, Farhadi-Pahnedari S

International journal of environmental health research

Curcumin

Alcohol Toxicity, Cognitive Decline/Dysfunction

Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

View abstract

In Vitro Study

Investigating the phytochemical composition of Curcuma longa, Azadirachta indica, and Asparagus racemosus using network pharmacology and molecular docking approaches for ovarian cancer therapy.

Sep 10, 2026 Santoshi S, Tanwar A, Bahri R, Aggrawal N, Ganjewala D, Bansal H

Zeitschrift fur Naturforschung. C, Journal of biosciences

Asparagus, Neem, Turmeric

Ovarian Cancer

Immunomodulatory, Chemotherapeutic

View abstract

Review

Curcumin in pancreatic cancer: A comprehensive review of anticancer mechanisms, EMT modulation, and clinical challenges.

Sep 10, 2026 Eftekhari H, Tajik Z, Ghafouri-Fard S

Cancer treatment and research communications

Curcumin

Pancreatic Cancer

Apoptotic, Chemosensitizer

View abstract

Animal Study

Calebin A mitigates oxidative stress and inflammation in diabetic nephropathy via Nrf2/HO-1 and NF-κB signaling pathways.

Sep 10, 2026 Vatanparast RG, Aliyari M, Yazdi MP, Alidadi S, Sokhanvar MR, Karav S, Kesharwani P, Hosseini H, Sahebkar A

Journal of diabetes investigation

Polyphenols, Turmeric

Diabetic Nephropathy

Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Renoprotective, Anti-Fibrotic, Nrf2 activation, Heme oxygenase-1 up-regulation

View abstract

In Vitro Study

Exploring the Potential of Calebin-A in Targeting Obesity-Related Genes and Pathways.

Sep 10, 2026 Mahmoudi A, Saeedi-Boroujeni A, Karav S, Kesharwani P, Sahebkar A

Journal of cellular and molecular medicine

Polyphenols, Turmeric

Obesity

Anti-Inflammatory Agents

View abstract

Animal Study

The turmeric polyphenol calebin A relaxes rat aorta through Ca(V)1.2 channel inhibition with evidence for K(Ca)1.1 channel involvement.

Sep 10, 2026 De Rosa F, Pettini F, Spiga O, Atanasov AG, Fusi F

Biochemical pharmacology

Polyphenols, Turmeric

Endothelial Dysfunction

Vasoprotective

View abstract

Animal Study

Network Pharmacology-Based Investigation of the Mechanism of Liupao Tea Polyphenol Extract in Preventing MAFLD via the Hepatic EGFR-AKT Pathway.

Sep 9, 2026 Wei J, He X, Shi T, Jin X, Huang J, Du Q, Huang J, Li T, Xie X, Huang Y, Nie C, Fan Y, Yang X, Song L, Tang W

Journal of agricultural and food chemistry

Black Tea

Fatty Liver

Antioxidants, Hypolipidemic

View abstract

Human Study

[Effects of different aging years of Liupao tea on metabolic indexes and body composition of overweight and obese people].

Sep 9, 2026 Hu Q, Wang Y, Chen B, Ma D

Wei sheng yan jiu = Journal of hygiene research

Black Tea

Overweight, Obesity

Hypolipidemic

View abstract

Animal Study

Liupao tea alleviates high-fat diet-induced obesity by re-establishing metabolic homeostasis of short-chain fatty acids and chenodeoxycholic acid.

Sep 9, 2026 Tan Y, Wang X, Song A, Xu S, Lin X, Yang B, Luo J, Tong Y, Wen M, Guan X, Li P, Luo Z, Zhu P, Chen G, Zhang Q

Food research international (Ottawa, Ont.)

Black Tea

Obesity, High Fat Diet

Gastrointestinal Agents, Hypolipidemic

View abstract

Review

Matcha as a Source of Bioactive Compounds: A Review of Health-Promoting Properties and Potential Applications.

Sep 9, 2026 Sławińska P, Raczkowska E

Nutrients

Green Tea, Matcha

Cancers: All, Inflammation, Obesity, Oxidative Stress, Cognitive Decline/Dysfunction

Anti-Inflammatory Agents, Antioxidants, Gastrointestinal Agents, Hypoglycemic Agents, Hypolipidemic

View abstract

Animal Study

Matcha green tea attenuates acrylamide-induced cerebellar damage in rats: Biochemical, histological and immunohistochemical study.

Sep 9, 2026 Essawy AS, Abo Elkhair DM

Tissue & cell

Green Tea, Matcha

Acrylamide-induced toxicity

Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Anti-Apoptotic, Acrylamide

View abstract