The addition of L. plantarum YHG-87 to sea buckthorn fermented milk provided enhanced protective effects against UC.
Sea Buckthorn Fermented Milk withYHG-87 Mitigates Symptoms of DSS-Induced Ulcerative Colitis Disease in Mice.
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Key Findings
Abstract
Ulcerative colitis (UC) is associated with gut microbiota imbalance, and probiotics may restore gut flora and improve intestinal health. Sea buckthorn, which is rich in antioxidants and anti-inflammatory compounds, may enhance these effects when combined with probiotics. In this study, we incorporated our screened strainYHG-87 (YHG-87) into sea buckthorn fermented milk to examine its additional benefits in a dextran sulfate sodium (DSS)-induced UC mouse model. Five groups (n = 6) were included: healthy control, DSS-induced colitis, regular fermented milk, sea buckthorn fermented milk, and sea buckthorn probiotic fermented milk (SC group). Results indicated that SC group significantly alleviated UC symptoms, such as weight loss, bloody stools, and colon shortening (
Affiliation
Ning Ju
External References
- PubMed ID:
- 41227760
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