Research Abstract
Azoxymethane-induced liver hemangiosarcomas in inbred strain-2 guinea pigs.
Narisawa T, Wong CQ, Weisburger JH
Journal of the National Cancer Institute
Mar 1, 1976
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Abstract
Intrarectal administration of 0.5 ml of a 0.2% solution of azoxymethane twice weekly for 33 weeks to female inbred strain-2 guinea pigs specifically induced multiple liver hemangiosarcomas in 15 of 16 animals 32-54 weeks after the first treatment. No neoplasms and preneoplastic changes were found in the large intestine.
External References
- PubMed ID:
- 943560
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