Research Abstract
Cell-cell interactions and erythropoiesis.
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Key Findings
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Abstract
The erythroblastic island, a distinct anatomical unit consisting of a central macrophage surrounded by a ring of erythroblasts, is a key feature of erythropoiesis in the bone marrow. While a number of functional sequelae for the interaction between the erythroblasts and macrophage have been suggested, much remains to be learned. We suggest that this interaction may play a role in regulated assembly of membrane proteins during erythroid differentiation.
Affiliation
Division of Cell and Molecular Biology, Lawrence Berkeley Laboratory, University of California, Berkeley 94720.
External References
- PubMed ID:
- 2018861
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