Devil's claw (H. procumbens) exhibits a uterotonic effect in the rat uterus, lending pharmacological credence to the suggested folkloric obstetric uses of the plant's secondary root for induction and/or acceleration of labour, as well as for expelling ret
Uterotonic effect of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract on rat isolated uterine horns.
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Abstract
Some traditional health practitioners of South Africa have claimed that Harpagophytum procumbens DC (family: Pedaliaceae) secondary root is a useful obstetric remedy for induction or acceleration of labour, as well as for expelling retained placentas in pregnant women. In the present study, therefore, we investigated the effect of H. procumbens secondary root aqueous extract (HPE) on longitudinal, tubular uterine horn muscle strips taken from non-pregnant and pregnant, young adult, female rats. HPE (10-800 microg/ml) induced concentration-related and significant (P
Affiliation
Department of Pharmacology, School of Pharmacy and Pharmacology, Faculty of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
External References
- PubMed ID:
- 19907121
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