Effects of Rosa roxburghii and kiwifruit composite supplements on improving exercise performance and anti-fatigue in mice.
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Abstract
Rosa roxburghii Tratt (RR) and Actinidia chinensis Planch (AC, kiwifruit) are nutrient-dense plant foods with diverse bioactive components. This study aimed to evaluate the effect of supplementation with Rosa roxburghii and Kiwifruit (RRAC)on improving the exercise performance-enhancing and anti-fatigue effects of a RR-AC composite supplement (RRAC) in experimental murine models. Fifty male institute of Cancer Research (ICR) mice were randomly allocated to five groups (n = 10/group): (1) the blank control group (Rest, normal saline), (2) the fatigue model control group (Con, normal saline), (3) RRAC-L (130 mg/kg/d), (4) RRAC-M (260 mg/kg/d), (5) RRAC-H (520 mg/kg/d). Following 28 consecutive days intervention, the mice in all groups except the Rest group underwent a swimming exhaustion test. Then, mice were subsequently euthanized for plasma biochemical markers and analysis and tissue collection. We found that supplementation with 28-day RRAC could significantly enhance mice's exercise endurance performance, elevated hepatic and muscle glycogen content (all p
Affiliation
Yuanyuan Wang
External References
- PubMed ID:
- 42315592
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