Galectin-3 inhibition with modified citrus pectin in hypertension.
Galectin-3 Inhibition With Modified Citrus Pectin in Hypertension.
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Key Findings
Abstract
We investigated the effect of galectin-3 (Gal-3) inhibition with modified citrus pectin on markers of collagen metabolism in a proof-of-concept randomized placebo-controlled trial of participants with elevated Gal-3 levels and hypertension. Although higher Gal-3 levels were associated with female sex, diabetes, and reduced glomerular filtration rate in cross-sectional analyses, treatment with modified citrus pectin did not change collagen markers. The effect of Gal-3 inhibition among individuals with heart failure warrants further investigation.
Affiliation
Emily S Lau
External References
- PubMed ID:
- 33532663
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