Glycyrrhizin, an active component of licorice roots, is superior to antiviral drugs in inhibiting SARS-associated coronavirus.
Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus.
AI Summary
Key Findings
Abstract
The outbreak of SARS warrants the search for antiviral compounds to treat the disease. At present, no specific treatment has been identified for SARS-associated coronavirus infection. We assessed the antiviral potential of ribavirin, 6-azauridine, pyrazofurin, mycophenolic acid, and glycyrrhizin against two clinical isolates of coronavirus (FFM-1 and FFM-2) from patients with SARS admitted to the clinical centre of Frankfurt University, Germany. Of all the compounds, glycyrrhizin was the most active in inhibiting replication of the SARS-associated virus. Our findings suggest that glycyrrhizin should be assessed for treatment of SARS.
External References
- PubMed ID:
- 12814717
Comments
Sign in or create a free account to join the conversation.
Sign in to commentBe the first to comment.