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Research Abstract Human Study

Glyphosate exposure, bone mineral density, osteoporosis, and fractures in the United States population.

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Abstract

PURPOSE: Following reports of an adverse link between glyphosate and bone mineral density (BMD), this cross-sectional study extended the investigation between glyphosate exposure and BMD to include osteoporosis, and fractures, with a focus on the high risk, post-menopausal female subgroup. METHODS: Cross-sectional data from 2,710 participants of the US National Health and Nutrition Examination Survey aged 8-59 years from 2013 to 2018 were used to assess associations between urinary glyphosate concentration (µg/L) and BMD (g/cm) was measured using dual-energy X-ray absorptiometry (DXA), while osteoporosis and fractures were self-reported. Linear and logistic regression analyses were adjusted for age, race/ethnicity, BMI, smoking status, and income. RESULTS: There was a negative association between glyphosate and BMD in the entire population (Whole Body BMD slope = -0.018; 95% CI = -0.027, -0.010; 

Affiliation

Naila Khalil

External References

PubMed ID:
41551845

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