Herbal formulation turmeric extract, black pepper, and ginger versus naproxen for chronic knee osteoarthritis.
Herbal formulation"turmeric extract, black pepper, and ginger"versus Naproxen for chronic knee osteoarthritis: A randomized, double-blind, controlled clinical trial.
AI Summary
Key Findings
Abstract
Osteoarthritis is the most common articular disease that can lead to chronic pain and severe disability. Curcumin-an effective ingredient in turmeric with anti inflammatory property-plays an important role in protecting the joints against destructive factors. Gingerols and piperine, are the effective ingredients of ginger and black pepper, which may potentially enhance and sustain the effect of curcumin in this direction. To determine the effect of cosupplementation with turmeric extract, black pepper, and ginger on prostaglandin E(PGE) in patients with chronic knee osteoarthritis, compared with Naproxen. Sixty patients with two different levels of knee osteoarthritis (Grade 2 and 3) were studied. Individuals were randomly assigned to receive daily turmeric extract, ginger, and black pepper together or Naproxen capsule for 4 weeks. PGEwas evaluated by ELISA method. 24-hr recall was also assessed. All of participants completed the study. PGEdecreased significantly in both groups (p
Affiliation
Motahar Heidari-Beni
External References
- PubMed ID:
- 32180294
Comments
Sign in or create a free account to join the conversation.
Sign in to commentBe the first to comment.