A herbal pair of Taraxacum officinale F.H.Wigg. and Lonicera japonica ameliorates obesity.
A Herbal Pair ofF.H.Wigg. andThunb. Ameliorates Obesity and Modulates AMPK Signaling.
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Key Findings
Abstract
Obesity is a complex metabolic disorder characterized by excessive fat accumulation and associated comorbidities. This study evaluated LIPO-700, a standardized herbal formulation combiningThunb. andF.H.Wigg., for its anti-obesity effects and underlying mechanisms. Network pharmacology and KEGG enrichment analyses identified AMPK signaling, adipocytokine signaling, and regulation of lipolysis among the top enriched pathways associated with the predicted targets of LIPO-700. In vitro, LIPO-700 significantly reduced lipid accumulation in differentiated 3T3-L1 adipocytes (up to 19.11% at 100 μg/mL,
Affiliation
Seong Chul Jin
External References
- PubMed ID:
- 42005319
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