Impact of beetroot juice on oxidative stress in untrained individuals.
Impact of beetroot juice on oxidative stress in untrained individuals: A systematic review and meta-analysis.
AI Summary
Key Findings
Abstract
Oxidative stress arises from an imbalance between reactive oxygen species and antioxidant defenses, contributing to chronic diseases. While extensively studied in athletes, its relevance in untrained individuals and the role of nutritional interventions such as beetroot juice (Beta vulgaris) (BRJ) remain less explored.To systematically evaluate the effects of BRJ on oxidative stress biomarkers and antioxidant capacity in non-athletic adults.A systematic review and meta-analysis were conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Cochrane guidelines. Experimental studies comparing BRJ to placebo in untrained adults, assessing redox biomarkers, were included. Risk of bias was assessed using RoB-2, certainty of evidence with GRADE, and pooled effects calculated using a random effects model.Seven studies (n = 360) met inclusion criteria. BRJ significantly reduced oxidative damage biomarkers (SMD = -0.42; 95% CI: -0.75 to -0.09; p = 0.01) with moderate heterogeneity (I = 55%), particularly improving the GSH/GSSG ratio. It also significantly increased total antioxidant capacity (SMD = 0.82; 95% CI: 0.36 to 1.27; p
Affiliation
Emmanuel Omar Ponce-Dávila
External References
- PubMed ID:
- 41642915
Comments
Sign in or create a free account to join the conversation.
Sign in to commentBe the first to comment.