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Research Abstract

Lymphadenosis benigna cutis resulting from Borrelia infection (Borrelia lymphocytoma).

Albrecht S, Hofstadter S, Artsob H, Chaban O, From L
Journal of the American Academy of Dermatology
Apr 1, 1991
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Abstract

Swelling and erythema of the right pinna developed in a 7-year-old girl. Six months later a biopsy specimen showed a dense, diffuse lymphoplasmacytic infiltrate involving most of the dermis except for a thin Grenz zone. The appearance was consistent with lymphocytoma cutis. She had been bitten by a tick on the right ear in Switzerland 6 weeks before the onset of the lesion. Serologic tests by enzyme-linked immunosorbent assay for Borrelia burgdorferi, done 6 and 11 months after the bite, yielded optical density readings of 1.04 and 0.65, respectively; indirect immunofluorescence yielded titers of 1:256 and 1:128. A Borrelia-like organism was identified by a modified Steiner stain; immunohistochemistry was noncontributory. The spirochetal origin of lymphadenosis benigna cutis is briefly reviewed.

Affiliation

Department of Pathology, Women's College Hospital, University of Toronto, Ontario, Canada.

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