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Research Abstract

Mutagenicity and toxicity of amitrole. II. Human lymphocyte culture tests.

Meretoja T, Gripenberg U, Bamford D, Laamanen I, Sorsa M
Mutation research
Jul 1, 1976
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1 min read
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Abstract

Effects of amitrole (3-amino-1,2,4-triazole) on human leucocytes in culture were investigated. Amitrole interfered with lymphoblast transformation and inhibited cell growth in concentrations of 0.2% w/v and higher. Selected metaphases were examined for the presence of chromosome and chromatid aberrations. No clastogenic effects were observed.

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