Noni has immunostimulatory activity on T and B lymphocytes, confirming its traditional use in the treatment of infections.
Immunostimulant activity of noni (Morinda citrifolia) on T and B lymphocytes.
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Key Findings
Abstract
Morinda citrifolia Linn (Rubiaceae) is a traditional medicinal herb that has been purported to be beneficial in the treatment of infections due to its immune enhancing properties. However, detailed studies highlighting the effect of different compounds isolated from the plant on the immune system are lacking. In this study, the stimulatory effects of the extracts and fractions of M. citrifolia fruits on important components of the adaptive immune system such as T lymphocytes and B lymphocytes were studied. The effects of the plant extracts on lymphocytes were assessed by in vitro (MTT assay) and in vivo (cell mediated immune response) techniques. Results of the MTT study indicated that the hydroalcoholic (0.5 and 1.0 mg/mL) and aqueous extracts (0.5 and 1.0 mg/mL) significantly (p
Affiliation
Department of Pharmacology, C.U. Shah College of Pharmacy, S.N.D.T. Women's University, Mumbai - 400 049, Maharashtra, India.
External References
- PubMed ID:
- 20645768
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