Peppermint has neuro-protective properties against gamma irradiation induced DNA fragmentation and apoptosis
Mentha piperita as a pivotal neuro-protective agent against gamma irradiation induced DNA fragmentation and apoptosis : Mentha extract as a neuroprotective against gamma irradiation.
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Key Findings
Abstract
Ionizing radiation is classified as a potent carcinogen, and its injury to living cells, in particular to DNA, is due to oxidative stress enhancing apoptotic cell death. Our present study aimed to characterize and semi-quantify the radiation-induced apoptosis in CNS and the activity of Mentha extracts as neuron-protective agent. Our results through flow cytometry exhibited the significant disturbance and arrest in cell cycle in % of M1: SubG1 phase, M2: G0/1 phase of diploid cycle, M3: S phase and M4: G2/M phase of cell cycle in brain tissue (p
Affiliation
Physiology Division, Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt, [email protected].
External References
- PubMed ID:
- 23011739
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