Research Abstract
In Vitro Study
Polyphenols from the medical mushroom Phellinus baumii inhibited H1N1, H5N1, and H3N2 neuraminidase activity.
Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii.
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Abstract
Five polyphenols were isolated from the ethanolic extract of the fruiting bodies of Phellinus baumii. These compounds were identified by various spectroscopic methods as hispidin, hypholomine B, inoscavin A, davallialactone, and phelligridin D. All compounds inhibited noncompetitively H1N1, H5N1, and H3N2 neuraminidase activity and reduced the amount of virally-induced cytopathic effect (CPE) according to an MDCK cell-based assay.
Affiliation
Byung Soon Hwang
External References
- PubMed ID:
- 26077494
Related Topics
Polyphenols
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Influenza A
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Medicinal Mushrooms
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Mushrooms: All
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Neurominidase Inhibitor
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H3N2 Infection
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H5N1 Infection
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Substance
Health Topic
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