Potassium chloride supplementation is associated with gastrointestinal lesions.
Upper gastrointestinal lesions after potassium chloride supplements: a controlled clinical trial.
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Key Findings
Abstract
The effects of a new microencapsulated potassium chloride formulation on upper gastrointestinal tract mucosa was compared with that of a popular wax-matrix formulation in 48 healthy volunteers. After a week of KCl, subjects were gastroscoped, the endoscopist being blind to the type of preparation taken. Wax-matrix formulations were associated with a higher incidence of upper gastrointestinal lesions. The lesions were not accompanied by epigastric symptoms. Glycopyrrolate, given to some volunteers to decrease gastric emptying, aggravated the effects of potassium chloride.
External References
- PubMed ID:
- 6127542
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