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Research Abstract Human Study

Propionyl-L-carnitine, L-arginine and niacin have value in erectile dysfunction.

Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a nutraceutical approach for erectile dysfunction.

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Abstract

The application of nutraceuticals in the field of male sexual function -in particular for erectile dysfunction (ED) - remains relatively under-explored. In a group of 54 unselected men (35-75 years), consecutively presenting to our ED clinic and naive to other ED treatments, we carried out a single-blind, one-arm study to evaluate the effects of a 3-month supplementation with propionyl-L-carnitine, L-arginine and niacin on their sexual performance. All patients had the short-international index of erectile function (IIEF) questionnaire, global assessment questions (GAQs) and routine laboratory testing, at baseline and 3 months afterward. 51 (92%) patients of 54 completed the entire study period. After 3 months of treatment, a small, but statistical significant improvement intotal and single items of the IIEF was found (Δ = 5.7 ± 4.1 P 

Affiliation

 Department of Experimental Medicine, Pathophysiology Section, Sapienza University of Rome, Rome, Italy;  INSERM U1060, CarMeN Laboratory, University Lyon, Lyon, France.

External References

PubMed ID:
21966881

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