Royal jelly and ω-3 could be helpful in Multiple sclerosis patients.
Study of Royal Jelly effect on serum levels of IL-4, TNF-α, TGF-B, and IFN-γin multiple sclerosis patients in comparison with Omega-3; A double-blind, randomized, clinical trial.
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Abstract
OBJECTIVE: Multiple sclerosis (MS) is a debilitating disorder related to damage to the central nervous system (CNS). MS incidence in about 2.3 million people worldwide. Royal jelly (RJ) is a white material with many medicinal properties. Omega-3 (ω-3) is a natural substance that its beneficial effects were demonstrated in several studies performed on MS patients. MATERIALS AND METHODS: 60 patients referring to the MS Society of Iran were randomly divided into two groups (1:1 ratio) receiving 1-gram RJ and 1-gramω-3 capsule 1 gr capsules of RJ and 1 grω-3 daily in addition to receiving their daily treatment. Then, their information was recorded. Blood samples of all subjects were collected to evaluate the level of IL-4, INF-Y, TGF-B, and TNF-αwith Enzyme-linked immunosorbent assay (ELISA) method twice; first, before the intervention and then, received supplements for one month. The duration of treatment was one month, and the patients returned to the center. RESULTS: The results indicated that RJ, similar toω-3, could improve the cytokines levels in MS patients. RJ significantly improved TNF-α(p
Affiliation
Nastaran Majdinasab
External References
- PubMed ID:
- 41647455
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