Research Abstract
[The effect of vinblastine on DNA metabolism in turnover cells (author's transl)].
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Abstract
Studies on the effect of Vinblastine on normal and tumour cell show that semi-conservative DNA synthesis correlates with the enzymatic activity of thymidine kinase. DNA repair investigations performed with Yoshida-Ascites cells indicate an inhibitory effect on the ligase system after Vinblastine treatment and gamma irradiation.
External References
- PubMed ID:
- 973390
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