Vitamin E may hold promise for the treatment of acantholysis.
High-dose tocopherol acetate therapy in epidermolysis bullosa siblings of the Cockayne-Touraine type.
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Key Findings
Abstract
We have employed a successful therapy for epidermolysis bullosa with high-dose oral tocopherol acetate. Two siblings with dominant dystrophic epidermolysis bullosa of the Cockayne-Touraine type were reported. Both siblings suffered from tense blisters and erosions healing with scars and transient milia on the extremities. Electron microscopic study of the blisters revealed a cleavage beneath the lamina densa in both siblings. High-dose oral tocopherol acetate therapy was administered to them with satisfactory clinical reduction of the blister formation.
External References
- PubMed ID:
- 8300945
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