This work confirms the antibacterial activity of CBD on Enterococcus spp.
Cannabidiol (CBD) and Other Cannabinoids as a Promising Alternative Antibacterial Agent-Pilot Study onandClinical Strains.
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Key Findings
Abstract
Gram-positive cocci of thegenus, despite their prevalence in the environment and the microbiota of healthy people, have become a serious threat in hospitals as opportunistic pathogens. These bacteria have many virulence factors and intrinsic resistance to existing drugs, which significantly narrows the group of effective antimicrobials. Due to the spread of Multi-Drug-Resistant (MDR) strains, there is a need to search for new substances as potential antibiotics. Our work aimed to evaluate the antimicrobial effect of commercially available products (five oils containing cannabidiol (CBD) and its derivatives and one 99% CBD product in the form of crystals) on 20 clinical strains ofandWe determined the Minimal Inhibitory Concentration (MIC) of CBD oils using the microdilution method in Mueller-Hinton broth (MHB). The CBD displayed antibacterial properties against all testedspp. strains (MIC≤1μg/mL). The higher concentration of CBD resulted in a larger antibacterial effect. The obtained MICs of pure CBD and CBD crystals were statistically lower (W = 97,
Affiliation
Zuzanna Kraszewska
External References
- PubMed ID:
- 41515438
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