Research Abstracts Database

Animal Study

Ginkgetin attenuates oxidative stress-induced apoptosis and osteoarthritis progression via the PI3K/Akt signaling pathway-mediated upregulation of Bcl-2.

Sep 12, 2026 Su W, Chen W, She H, Song Y, Song Q, Yuan H, Chen L, Chen W, Pang QQ, Wei P

Journal of ethnopharmacology

Ginkgo biloba

Osteoarthritis

Antioxidants, Anti-Apoptotic, Chondroprotective

View abstract

Animal Study

Ginkgetin Alleviates Doxorubicin-Induced Heart Failure by Regulating Mitochondrial Dysfunction Through the AMPK/Sirt1/NF-κB Signaling Pathway.

Sep 12, 2026 Wang Y, Wang C, Li W, Ren X, Peng Y, Zhang Y

Balkan medical journal

Ginkgo biloba

Chemotherapy-Induced Toxicity: Doxorubicin

Antioxidants, Cardioprotective, Glutathione Upregulation, SIRT1 Activator, Superoxide Dismutase Up-regulation, Malondialdehyde Down-regulation, Chemoprotective Agents

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In Vitro Study

Ginkgetin alleviates sepsis-induced acute lung injury by promoting autophagy via inhibiting ubiquitination of Laptm5 in macrophages.

Sep 12, 2026 Liang H, Yuan Z, Liu R, Hu H, Chen Q, Lin Z, Gu Z, Qiu Y, Wang Q, Zhu B, Deng Y, Huang S, Peng Z, Zhang X, Liu Y

Phytomedicine : international journal of phytotherapy and phytopharmacology

Ginkgo biloba

Sepsis, Lung Damage

Anti-Inflammatory Agents, Autophagy Up-regulation

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In Vitro Study

Ginkgetin inhibits non-small cell lung cancer via the HSP90-AKT signaling pathway.

Sep 12, 2026 Li R, Gao H, Wang M, Zhang Y

Naunyn-Schmiedeberg's archives of pharmacology

Ginkgo biloba

Non-Small-Cell Lung Carcinoma

Antiproliferative, Anti-metastatic

View abstract

In Vitro Study

Ginkgetin alleviates UV-induced skin photoaging by reducing oxidative stress and promoting DNA repair via AKT-mediated homologous recombination repair.

Sep 12, 2026 Zhao Y, Zhou L, Shen S, Yin X, Chang Q, Yan Y, Li C, Cao Z, Zhang H, Zeng Q, Wang X, Wang P

Journal of photochemistry and photobiology. B, Biology

Ginkgo biloba

Ultraviolet Radiation Induced Damage

Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-1 (MMP-1) inhibitor, Photoprotective

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In Vitro Study

Ginkgetin targets GRP78 to induce dual pathways of ER stress and immune activation in osteosarcoma.

Sep 12, 2026 Xu W, Liu T, Ma X, Dong H, Cao Y, Li G, Wang Z, Hua Y, Cai Z, Sun M, Li J, Zhang T

Oncogene

Ginkgo biloba

Osteosarcoma

Immunomodulatory, Apoptotic, Autophagy Up-regulation

View abstract

Animal Study

Ginkgetin alleviates cisplatin-induced muscle atrophy via inhibition of the macrophage cGAS-STING pathway.

Sep 12, 2026 Chen X, Lin J, Lv J, Wen L, Wang Q, Jiang D

Biochemical pharmacology

Ginkgo biloba

Chemotherapy-Induced Toxicity: Cisplatin, Muscle Atrophy

Chemoprotective Agents

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Animal Study

Ginkgetin enhances the antitumor effect of Taxol on human breast cancer MCF-7 cells via ferroptosis mediated by the MDM2-p53-YAP1 axis.

Sep 12, 2026 Li G, Yan W, Peng X, Yin Z, Mahati S

Scientific reports

Ginkgo biloba

Breast Cancer

Antiproliferative, Tumor Suppressor Protein p53 Upregulation

View abstract

Review

Ginkgetin: A Promising Multitarget Agent for Diverse Diseases.

Sep 12, 2026 Sun Z, Rao Z, Lu Y, Zheng X, Zheng L

Biomolecules

Ginkgo biloba

Cancers: All, Cardiovascular Diseases, Inflammation, Metabolic Diseases, Musculoskeletal Diseases, Oxidative Stress

Anti-Bacterial Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Cardioprotective, Anti-Fibrotic, Nrf2 activation, Heme oxygenase-1 up-regulation

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Animal Study

Ginkgetin Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting the Nuclear Factor Kappa B Pathway.

Sep 12, 2026 Qiao X, Xie W, Ding Y, Shan L

Chemical biology & drug design

Ginkgo biloba

Colitis

Anti-Inflammatory Agents, Gastrointestinal Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor, NF-kappaB Inhibitor, Interleukin-6 Downregulation, Interleukin-1 beta downregulation

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Research

Gas therapy: an innovative application for intervertebral disc degeneration.

Sep 1, 2026 Cai L, Ru B, Ren H, Cai F, Zeng L, Yang J, Wang S, Zhang H, Li Y, Zhang L

Medical gas research

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Animal Study

Ganoderic acid A alleviates metabolic dysfunction-associated fatty liver disease through attenuating steatosis.

Jul 3, 2026 Yang Yao, Zhujun Liu, Xujiao Wang, Cunhao Bian, Na Yin, Xiaoyu Peng, Siqian Qin, Rui Wang, Yukun Zhang

Int Immunopharmacol

Reishi Mushroom

Nonalcoholic fatty liver disease (NAFLD)

Hypolipidemic

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Animal Study

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice.

Jun 30, 2026 Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang

Int J Mol Med

Reishi Mushroom

Hyperlipidemia

Gastrointestinal Agents, Hepatoprotective

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Animal Study

Ginsenoside Rg3 ameliorates di-(2-ethylhexyl) phthalate-induced spermatogenic impairment.

Jun 30, 2026 Xu-Fei Gao, Nan Ma, Yu-Zhuo Zhang, Jing Zhang, Zhi Liu, Hong-Yan Zhu, Xiao-Jie Gong, Yin-Shi Sun, Di Qu, Jun-Nan Hu, Zi Wang, Wei Li

J Environ Sci (China)

Ginsenosides

Oxidative Stress, Phthalate Toxicity

Antioxidants, Anti-Apoptotic, Phthalates

View abstract

In Vitro Study

Gambogic acid induces cell death via covalent binding with PRDX1 to regulate ER stress and autophagy.

Jun 2, 2026 Jinyan Wang, Wei Zhang, Li Yang, Xiaoru Zhong, Jinhuan Ou, Ashok Iyaswamy, Xin Gu, Chuanbin Yang, Bing Guo, Mingjun Shi, Jigang Wang

Chin Med

Gambogic Acid

Kidney Cancer

Apoptotic

View abstract

Research

Genetic susceptibility to type 2 diabetes: Insights from a comprehensive meta-analysis of polymorphisms.

Jun 1, 2026 Anilkumar AS, Thomas SM, Veerabathiran R

Journal of diabetes and metabolic disorders

View abstract

Research

Genetic insights into hepatitis E virus through environmental surveillance in Europe.

Jun 1, 2026 Wang H, Patzi-Churqui M, Andius LD, Nyström K, Lagging M

One health (Amsterdam, Netherlands)

View abstract

Research

GLP-1 receptor agonists in kidney transplant recipients with type 2 diabetes mellitus: a systematic review and meta-analysis on mortality and major adverse kidney events.

Jun 1, 2026 Aliyeva T, Natche J, Jiakponna EC, Ahmad F, Eze B, Nawaz UH, El-Amri I, Shrestha S

Journal of diabetes and metabolic disorders

View abstract

Research

Glycated CD59: an emerging biomarker of diabetic nephropathy associated with microalbuminuria, tubular damage, and complement activation.

Jun 1, 2026 Chinta B, Padma S, Ambati RR

Journal of diabetes and metabolic disorders

View abstract

Research

General self-efficacy in East and West Germany: A comparison of two German representative cohorts in 2014 and 2022.

Jun 1, 2026 Reinwarth AC, Petersen J, Beutel ME, Weidner K, Clemens V, Brähler E

Public health in practice (Oxford, England)

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Research

Ground-based travel to European academic events as an alternative to air travel: Estimating associated greenhouse gas emissions, time and cost.

Jun 1, 2026 Grech J, Richards DA

Public health in practice (Oxford, England)

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Research

Gold-incorporated hyaluronic acid nanoparticles enhance ablative radiotherapy efficacy in lung cancer.

Jun 1, 2026 Chen JL, Yang SJ, Lin LC, Pan CK, Tsai CY, Huang YS, Chen KC, Shieh MJ, Lin YL

International journal of pharmaceutics: X

View abstract

Research

Genetic dissection of gluten characteristics based on single- and multi-locus genome-wide association studies in wheat ( L.).

Jun 1, 2026 Jiang X, Li Q, Geng Y, Zhao J, Li Y, Li H

Food chemistry. Molecular sciences

View abstract

Research

Genomic epidemiology of and its monophasic variants in Southern China: A spatiotemporal and source attribution analysis.

Jun 1, 2026 Liao N, Lei S, Liu C, Tang S, Peng S

One health (Amsterdam, Netherlands)

View abstract