Research Abstracts Database

Animal Study

Lead Validation of the Olive Phenolic S-(-)-Oleocanthal for Effective Control of KRAS(G13D)-Mutant Colorectal Cancer Progression and Metastasis.

Sep 12, 2026 Tarun MTI, Ebrahim HY, El Sayed KA

Nutrients

Oleocanthal

Colorectal Cancer

Antiproliferative, Anti-metastatic

View abstract

Animal Study

Liupao tea alleviates high-fat diet-induced obesity by re-establishing metabolic homeostasis of short-chain fatty acids and chenodeoxycholic acid.

Sep 9, 2026 Tan Y, Wang X, Song A, Xu S, Lin X, Yang B, Luo J, Tong Y, Wen M, Guan X, Li P, Luo Z, Zhu P, Chen G, Zhang Q

Food research international (Ottawa, Ont.)

Black Tea

Obesity, High Fat Diet

Gastrointestinal Agents, Hypolipidemic

View abstract

In Vitro Study

Low-dose Andrographolide Synergizes With Cytarabine or Vincristine in Plasma Cell Neoplasm Cell Lines.

Sep 4, 2026 Doi H, Akiyama H, Matsui T, Abe Y, Fujii S, Matsuura H, Miura Y

Anticancer research

Andrographolide

Multiple Myeloma

Apoptotic

View abstract

In Vitro Study

Lucidumones L-P: Meroterpenoids from Ganoderma lucidum and their inhibitory effect on triple negative breast cancer.

Aug 31, 2026 Jiao-Jiao Zhang, Ze-Hong Wu, Yuan-Nan Yuan, Dan Cai, Jia-Wang Liu, Hong Zhou, Zhong-Hui Yang, Yan-Jiao Yin, Yong-Xian Cheng

Phytochemistry

Reishi Mushroom

Breast Cancer: Triple Negative

Antiproliferative

View abstract

Animal Study

Liposomal honokiol attenuates dimethylhydrazine-induced colon carcinogenesis in rats through modulation of oxidative stress, inflammation, apoptosis, autophagy, and lipid metabolism pathways.

Aug 13, 2026 Kattan SW, Almars AI, Elmorsy EM, Al-Ghafari AB, Al Doghaither HA, Elwakeel EE, Alawam MK, Elshopakey GE

Medical oncology (Northwood, London, England)

Honokiol

Colorectal Cancer

Anti-Inflammatory Agents, Antioxidants, Apoptotic, Chemopreventive

View abstract

Animal Study

Lung-Targeted Lipid Nanoparticles Delivery of Wogonin for Pulmonary Fibrosis in Mice via Modulation of Cellular Proteostasis.

Aug 12, 2026 Wang L, Lin F, Gao F, Jia Z, Liu J, Liu X, Shang J, Ru X, Zhao Y, Zhao T, Yang L, Guo Y, Zhang M

International journal of nanomedicine

Wogonin

Pulmonary Fibrosis

Anti-Fibrotic

View abstract

Animal Study

Long-term low-dose nanoplastic exposure induces neurotoxicity with oxidative brain damage.

Jul 31, 2026 Peifei Ying, Qixue Bao, Yilin Jiang, Tianyuan Chen, Zeyan Li, Yonghao Sun, Ling Zhang

Food Chem Toxicol

Oxidative Stress, Neurodegenerative Diseases, Brain: Microglial Activation, Microplastic Toxicity

Malondialdehyde Down-regulation, Nano Plastic-and Micro-Particles

View abstract

Animal Study

Lutein and zeaxanthin provide protection against aflatoxin B1-induced liver and kidney toxicity.

Jul 12, 2026 Solomon Owumi, Joseph Chimezie, James A Owolabi, Jesse C Nwaokolo, Esther M Pius, Abdullah A Sanusi, Ifeoluwa O Alabi, Jesutosin O Babalola, Victor O Eso, Hikmah Abdulganiyu, Oluwaseun M Owolabi, Olatunde Owoeye

Mycotoxin Res

Lutein, Zeaxanthin

Liver Damage: Aflatoxin-Induced

Hepatoprotective, Renoprotective, Aflatoxin

View abstract

Animal Study

Licochalcone A from Ma-Xing-Shi-Gan decoction to prevent Asthma.

Jun 14, 2026 Yunyun Dai, Hefeng Yao, Zihan Yang, Junyang Wang, Leyi Yin, Wei Mao

Int Immunopharmacol

Licorice

Asthma

Anti-Asthmatic Agents

View abstract

In Vitro Study

Linking di-2-ethylhexyl phthalate (DEHP) exposure to osteoporosis through population analysis, network toxicology, and experimental evidence.

Jun 14, 2026 Liji Li, Zhiwen Liu, Xinyue Luo, Haoliang Chen, Danfeng Wang, Liang Zeng, Zhuoda Tang

Exp Gerontol

Osteoporosis, Phthalate Toxicity

Phthalates

View abstract

Research

Ligand-modified liposomes as drug delivery systems for the active targeting of pancreatic cancer.

Jun 1, 2026 Jang Y, Jang J, Son J, Lee HY, Choi J

International journal of pharmaceutics: X

View abstract

Research

Living beyond survival: Experiences of self-management among long-term breast cancer survivors - A qualitative study.

Jun 1, 2026 Liu X, Yang M, Ma Y

International journal of nursing studies advances

View abstract

Research

Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.

Jun 1, 2026 Zhao Q, Zhang HJ, Han MM, Abiti J, Dong YJ, Wang JN, Lu JT, Wang W, Zhang X, Geng SL, Qiu LL, Wang XY, Hua ZC, Wang TY, Jia YL

Synthetic and systems biotechnology

View abstract

Research

Liposomal antimicrobials in the fight against bacterial and fungal pathogens: Clinical successes and development challenges.

Jun 1, 2026 Kenaan HT, Duncan RM, Al-Jamal WT, Jones DS, Andrews GP, Gilmore B, Yardley V, Farrington N, Stott KE, Lawrence D, Jarvis JN, Harrison TS, Robinson S, Ribeiro I, Hope W, Tian Y

International journal of pharmaceutics: X

View abstract

Animal Study

Low-dose epigallocatechin gallate combined with L-theanine effectively alleviate obesity and metabolic dysfunction-associated steatotic liver disease.

May 31, 2026 Gaolong Zuo, Yujie Shen, Ling Wang, Yu Gao, Chenyi Luo, Juanshu Wen, Jie Li, Jian-An Huang, Zhonghua Liu, Yong Lin

Phytomedicine

EGCG (Epigallocatechin gallate), Theanine

Fatty Liver, Obesity, Oxidative Stress

Gastrointestinal Agents, Hepatoprotective

View abstract

In Vitro Study

Liquiritin inhibits LPS-ATP-induced H9c2 cell inflammation damage.

May 31, 2026 Lan Zhou, Yi-Fang Deng, Lu-Qin Guo, Liang Wang, Peng Zhou

Tissue Cell

Licorice

Inflammation, Myocardial Infarction, Lipopolysaccharide-Induced Toxicity

Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-18 down-regulation

View abstract

In Vitro Study

Long-term exposure to polystyrene microplastics exacerbates seizure symptoms via lipid metabolic disruption and ferroptosis.

May 28, 2026 Yueying Liu, Ruijin Xie, Wenjing Zhao, Hua Xu, Jianrui Dou, Xue Xiao, Yufan Luo, Heng Zhang, Peiweng Wang, Wei Xiao, Xiao Tong, Shengjie Xu, Dongqin Wu, Xianhui Deng, Yu Wu, Chenyu Sun, Shudong Hu

J Nanobiotechnology

Seizures, Microplastic Toxicity

Polystyrene nanoparticles, Nano Plastic-and Micro-Particles

View abstract

Human Study

Long-term efficacy of psilocybin with adjunct psychotherapy in treatment-resistant major depression.

May 26, 2026 Lea J Mertens, Felix Betzler, Manuela Brand, Ricarda Evens, Andrea Jungaberle, Henrik Jungaberle, Laura Kärtner, Tomislav Majić, Christian N Schmitz, Andreas Ströhle, Dennis Scharf, Moritz Spangemacher, Max Wolff, Zahra Assadi, Scharif Bahri, Lilith Becher, Luca V Färber, Henry Harder, Niklas Kirchen, Eugenia Kulakova, Linda C Kunz, Andy Meijer, Barbara Rohrmoser, Stefan Wellek, Moritz M Berger, Michael Koslowski, Gerhard Gründer

Psychother Psychosom

Psilocybin

Depression

Antidepressive Agents

View abstract

Animal Study

Lacticaseibacillus casei Zhang modulates iron homeostasis in iron-overloaded mice via an IL-22-dependent pathways.

May 25, 2026 Feiyan Zhao, Da Ma, Yinyin Gao, Luping Yang, Lu Gao, Zhihong Sun

NPJ Sci Food

Lactobacillus casei

Iron Overload

Interleukin-22 Downregulation

View abstract

Research

LRP-1/CD44-targeted regorafenib nano-delivery system leveraging anti-angiogenesis and synergistic cytotoxicity against peritoneal metastasis of colorectal cancer.

May 1, 2026 Qian Y, Wang M, Li Y, Zhu M, Pan M, Li X, Chen W, Wei Y, Li R, Hu D, Qian Z

Bioactive materials

View abstract

Research

Lactate and lactylation modifications in neurological disorders.

May 1, 2026 Gu Y, Chen K, Lei C, Yang X, Wang L, Zhao L, Jiang W, Deng Q

Neural regeneration research

View abstract

Research

Low-AC-Loss Nb3Sn Validation Model Coil in Solid Nitrogen for a Fast-Switching-Field MRI Magnet Prototype.

May 1, 2026 Hu J, Kim J, Shao L, Bascuñán J, Iwasa Y, Ackerman JL, Park D

IEEE transactions on applied superconductivity : a publication of the IEEE Superconductivity Committee

View abstract

Research

Lnc_011797 promotes ferroptosis and aggravates white matter lesions.

May 1, 2026 Xu X, Sun Y, Zhu X, Ma S, Wei J, He C, Chen J, Pan X

Neural regeneration research

View abstract

Research

Latest progress and challenges in drug development for degenerative motor neuron diseases.

May 1, 2026 Wen X, Lan T, Su W, Cao B, Wang Y, Chen Y

Neural regeneration research

View abstract