Research Abstracts - GreenMedInfo

Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Interleukin-6 Downregulation, Interleukin-1 beta downregulation, Interleukin-17 downregulation

View abstract

Animal Study

Protective effects of Perilla frutescens seed oil on cognitive function, oxidative stress and acetylcholinesterase activity in a D-galactose-induced accelerated aging model in rats.

Aug 21, 2026 Jeefoo WP, Thongrong S, Kangwan N, Pohsa S, Kangwan J, Kobroob A, Somka R

Biomedical reports

Perilla

Aging, Cognitive Decline/Dysfunction

Antioxidants, Neuroprotective Agents, Acetylcholinesterase Inhibitor

View abstract

Animal Study

Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice.

Aug 21, 2026 Wang J, He Y, Yu D, Jin L, Gong X, Zhang B

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Perilla

Diabetes Mellitus: Type 2, Insulin Resistance

Gastrointestinal Agents, Insulin Sensitizers

View abstract

Animal Study

Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice.

Aug 21, 2026 Xiao Y, Xiao L, Li M, Liu S, Wang Y, Huang L, Liu S, Jiang T, Zhou L, Li Y

Food & function

Perilla

Fatty Liver, Obesity, High Fat Diet

Hypolipidemic

View abstract

Animal Study

Physicochemical characterization, lipid-metabolism effects and transcriptomics insights of perilla seed oil in high-fat-diet induced rats.

Aug 21, 2026 Hu P, Zhang B, Fatima Z, Liu Y, Li L, Ai P, Yang X, Li L, Chang J

Journal of ethnopharmacology

Perilla

Hyperlipidemia, High Fat Diet

Hypolipidemic

View abstract

Human Study

Perilla extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study.

Aug 21, 2026 Buchwald-Werner S, Fujii H, Reule C, Schoen C

BMC complementary and alternative medicine

Perilla

Bloating

Gastrointestinal Agents

View abstract

In Vitro Study

Piperine-loaded solid lipid nanoparticles: a promising nano-phytomedicine for the treatment of non-alcoholic fatty liver disease.

Aug 20, 2026 Moin A, Ram S, Boregowda SS, Hussain T, Abu Lila AS, Jayaramu RA, Rizvi SMD, Anwar S, Chandan K

Frontiers in pharmacology

Piperine

Nonalcoholic fatty liver disease (NAFLD)

Hepatoprotective

View abstract

Research Abstracts Database

Abstracts Starting with "P"

Protective effects of icariin-loaded nanoliposomes against methotrexate-induced testicular toxicity via modulation of NRF2/NF-κB and ferroptosis signaling.

Protective Role of Apigenin-PEGylated Chitosan Nanoparticles Against Pesticide Deltamethrin-Induced Liver Injury via Antioxidant Activation, NF-κB Inhibition, and Bcl-2/Bax/Caspase-3 Signaling Modulation.

Passion Fruit Seed Oil as a Natural Tyrosinase Inhibitor: Extraction Optimization, Multi-Mechanism Elucidation, and Efficacy Validation in Zebrafish.

Protective effects of Passiflora edulis Sims peel fermentation polysaccharide against UVB-induced photodamage via antioxidant and anti-inflammatory activities.

Perillaldehyde Attenuates Insulin Resistance and High Glucose-Induced Ferroptosis in Trophoblast Cells via Regulation of PTPN1/Akt/Foxo1 Signaling Pathway.

Perillaldehyde-Encapsulated Lipid Nanoparticle Hydrogel for Enhanced Wound Healing, Improved Stability and Biocompatibility.

Perillaldehyde inhibits oxidative stress, NLRP3-mediated inflammation and fibrosis in diabetic nephropathy through regulating HMOX1.

Perillaldehyde Attenuates Diabetic Nephropathy through Modulation of the Nrf2/Keap1 and NF-κB Signalling Pathways.

Perillaldehyde alleviates Parkinson's disease via the gut microbiota-5-methyltetrahydrofolate-homocysteine methylation axis.

Protective effect of extracts of Perilla frutescens treated with sucrose on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in vitro and in vivo.

Perilla frutescens leaf extract inhibits mite major allergen Der p 2-induced gene expression of pro-allergic and pro-inflammatory cytokines in human bronchial epithelial cell BEAS-2B.

Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages.

Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.

Purple perilla frutescens extracts containing α-asarone inhibit inflammatory atheroma formation and promote hepatic HDL cholesterol uptake in dyslipidemic apoE-deficient mice.

Perillaldehyde reduces mitochondrial oxidative stress damage by regulating KCNT2/NR1D1 protein activity in vascular dementia rats.

Protective Effect of Thai Perilla frutescens Seed Oil Against Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke Extract in a Mouse Model.

Protective effect of aqueous extract of Perilla frutescens on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in rats.

Perilla frutescens extract ameliorates DSS-induced colitis by suppressing proinflammatory cytokines and inducing anti-inflammatory cytokines.

Protective effects of Perilla frutescens seed oil on cognitive function, oxidative stress and acetylcholinesterase activity in a D-galactose-induced accelerated aging model in rats.

Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice.

Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice.

Physicochemical characterization, lipid-metabolism effects and transcriptomics insights of perilla seed oil in high-fat-diet induced rats.

Perilla extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study.

Piperine-loaded solid lipid nanoparticles: a promising nano-phytomedicine for the treatment of non-alcoholic fatty liver disease.