Research Abstracts - GreenMedInfo

In Vitro Study

Therapeutic effects of ginkgetin on rheumatoid arthritis: evidence from network pharmacology and experimental validation.

Sep 12, 2026 Zhao C, Yu H, Wang J, Xu K, Yang M, Xu P

Clinical rheumatology

Ginkgo biloba

Arthritis: Rheumatoid

Anti-Inflammatory Agents, Apoptotic, Antiproliferative, Interleukin-6 Downregulation, Interleukin-1 beta downregulation, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Animal Study

The Effect of Curcumin on Carbon Tetrachloride-Induced Lung Injury.

Sep 12, 2026 Atalay Ş, Keçeci M, Akpolat Ferah M, Babaoğlu E

Biomedicines

Curcumin

Lung Damage

Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Interleukin-1 beta downregulation, Transforming growth factor beta (TGF-β) inhibitor

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Animal Study

Therapeutic and prophylactic roles of oleuropein in experimental acute lung injury: Modulation of tumor necrosis factor-α and nuclear factor erythroid 2-related factor 2 pathways.

Sep 12, 2026 Kurak TU, Bahar L, Çelik Ç, Büyükafşar K, Aydin T, Köksel MO

Experimental and therapeutic medicine

Oleuropein

Acute Respiratory Distress Syndrome

Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Nrf2 activation, Prophylactic Agents

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Review

The Mechanism of Icariin in Regulating BMSCs for Treating Osteoporosis: A Review.

Sep 11, 2026 Wang C, Wu Z, Xu Y, Li Y, Man Z, Liu K, Wang J, Lin W, Qie F, Shi X, Yuan Y

Endocrine, metabolic & immune disorders drug targets

Icariin

Osteoporosis

Osteogenic, Wnt/β-catenin signaling pathway modulation

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Review

The Use of Curcumin to Target Oxidative Stress and Inflammation in Type 2 Diabetes Mellitus and Its Complications: Molecular Mechanisms and Therapeutic Perspectives.

Sep 10, 2026 Zhang J, Shu Q, Tang Y, Liu H, Zhang C, Chen X, Li S

Antioxidants (Basel, Switzerland)

Curcumin

Diabetes Mellitus: Type 2, Advanced Glycation End products (AGE)

Anti-Inflammatory Agents, Antioxidants, Gastrointestinal Agents, NF-kappaB Inhibitor, Insulin Sensitizers, Anti-Glycation Agents

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Animal Study

The turmeric polyphenol calebin A relaxes rat aorta through Ca(V)1.2 channel inhibition with evidence for K(Ca)1.1 channel involvement.

Sep 10, 2026 De Rosa F, Pettini F, Spiga O, Atanasov AG, Fusi F

Biochemical pharmacology

Polyphenols, Turmeric

Endothelial Dysfunction

Vasoprotective

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In Vitro Study

Theaflavins counteract free fatty acid-driven oxidative-inflammatory injury in endothelial cells through Nrf2-NF-κB axis.

Sep 9, 2026 Zhao Y, Qu B

Frontiers in immunology

Theaflavins

Inflammation, Oxidative Stress

Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Nrf2 activation

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Human Study

Tai Chi exercise improves sleep quality in older adults with mild insomnia by enhancing slow-wave activity during deep sleep: a 12-week randomized controlled trial.

Sep 8, 2026 Lyu M, Cheng J, Li J

Frontiers in physiology

Insomnia

Tai Chi

View abstract

Human Study

Tai Chi Intervention Improves Hypertension by Reshaping the Neuro-Endocrine-Immune Network via the Acetylcholine-Cortisol-TNF-α Pathway.

Sep 8, 2026 Fang H, Li C, Zhou Q, Cui M, Li L, Lyu S, Zhang J

Scandinavian journal of medicine & science in sports

Hypertension

Antihypertensive Agents, Tai Chi

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Animal Study

The inhibition of deep peritoneal endometriosis by Andrographolide through macrophage M1 activity in an endometriosis mice model.

Sep 7, 2026 Susianto IA, Susilaningsih N, Hidayat ST, Hardian, Tjandrawinata RR, Rachmawati B

Veterinarni medicina

Andrographolide

Endometriosis

Anti-Inflammatory Agents, Immunomodulatory

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Research

Therapeutic potential of nitric oxide and its donors in hemorrhagic and ischemic stroke: a systematic review.

Sep 1, 2026 Wang S, Wan S, Zhang X, Sun M, Li H, Chen G, Wang J, Li X

Medical gas research

View abstract

In Vitro Study

The influence of in vitro gastrointestinal digestion on the Perilla frutescens leaf extract: Changes in the active compounds and bioactivities.

Aug 25, 2026 Wang ZX, Lin QQ, Tu ZC, Zhang L

Journal of food biochemistry

Perilla

Alzheimer's Disease, Breast Cancer, Diabetes Mellitus: Type 2

Antioxidants, Antiproliferative, Alpha-glucosidase inhibitor

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Review

The mechanism of perilla oil in regulating lipid metabolism.

Aug 21, 2026 Xia J, Wang Y, Li X, Liu L, Zhang P, Dai W, Luo P, Wang G, Li Y

Food chemistry

Perilla

Hyperlipidemia

Hypolipidemic

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Meta Analysis

The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.

Aug 20, 2026 Liu S, Yao W, Wei Y, Azhati S, Wu Y, Zhong W, Wang P, Dai H, Zhao K, Liu C

Nutrients

Astaxanthin

Athletic Performance

Exercise

View abstract

Human Study

The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial.

Aug 19, 2026 Amini S, Dehghani A, Sahebkar A, Iraj B, Rezaeian-Ramsheh A, Askari G, Majeed M, Bagherniya M

International journal of preventive medicine

Piperine, Curcumin

Diabetic Retinopathy

View abstract

Human Study

Topical Piperine for the Management of Burning Mouth Syndrome: A Case Series.

Aug 19, 2026 Varoni EM, Meregalli M, Lodi G, Vitalini S, Iriti M, Sardella A

Journal of clinical medicine

Piperine

Burning Mouth Syndrome

View abstract

Meta Analysis

The Effect of Nigella sativa Supplementation on Cardiometabolic Health in Patients With Metabolic Diseases: A GRADE-Assessed Systematic Review and Meta-Analysis.

Aug 19, 2026 Musazadeh V, Jahangir M, Mahmoudinezhad M, Faghfouri AH, Teymoori F, Anoushirvani AA, Khaleghian M

Endocrinology, diabetes & metabolism

Nigella sativa (aka Black Seed)

Metabolic Diseases

Cardioprotective

View abstract

In Vitro Study

Thymoquinone combined with conventional antibiotics against pandrug-resistant Staphylococcus aureus: a pharmacodynamic and molecular simulation strategy to overcome bioavailability limitations.

Aug 19, 2026 Ahmad AAM, El-Naenaeey EYM, Elmowalid GA, Khamis T, Kandel TA, Khodeer DM, Orfali R, Abd El-Hamid MI

Frontiers in pharmacology

Thymoquinone

Staphylococcus aureus infection

Anti-Bacterial Agents

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Animal Study

Therapeutic evaluation of phytochemicals present in Nigella sativa seed oil for anxiolytic activity against the GABA-B receptor: a gas chromatography-mass spectrometry (GC-MS)-supported molecular dynamics-based in silico study.

Aug 19, 2026 Khan A, Ansari MS, Khan AA, Abbas K, Alam M

In silico pharmacology

Nigella sativa (aka Black Seed)

Anxiety

Anti-Anxiety Agents

View abstract

In Vitro Study

Thymoquinone Enhances Tamoxifen Efficacy Against Triple-Negative Breast Cancer by Targeting EMT Signaling.

Aug 19, 2026 Haque M, Shyanti RK, Sharma S, Wu H, Mishra MK

International journal of breast cancer

Thymoquinone

Breast Cancer, Breast Cancer: Triple Negative

Chemotherapeutic

View abstract

Animal Study

Thymoquinone enhances kidney function in obesity-induced renal impairment by targeting redox balance, inflammation, autophagy, and apoptosis.

Aug 19, 2026 Mostafa MD, Amer ME, Elkomy MA, Othman AI, El-Missiry MA

Tissue & cell

Thymoquinone

Obesity, High Fat Diet

Anti-Inflammatory Agents, Antioxidants, Renoprotective

View abstract

Review

Thymoquinone in Atherosclerosis: A Multi-Target Nutraceutical Modulating Inflammation, Oxidative Stress, and Lipid Metabolism.

Aug 19, 2026 Fic W, Kwaśniewska K, Polak-Szczybyło E

Nutrients

Thymoquinone

Atherosclerosis

Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor, NF-kappaB Inhibitor, Interleukin-6 Downregulation, Interleukin-1 beta downregulation, Anti-atherogenic

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Animal Study

Thymoquinone and caffeic acid phenethyl ester mitigate experimental ulcerative colitis: a biochemical and histopathological study.

Aug 19, 2026 Ersak C, Ergüder E, Nojadeh JN, Altiner S, Pekcici MR

Acta cirurgica brasileira

Caffeic acid phenethyl ester, Thymoquinone

Ulcerative Colitis

Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

View abstract

In Vitro Study

The Effects of Neurotropic B Vitamins, Vitamin D3, and Alpha-Lipoic Acid in In Vitro Models of Neurodegeneration.

Aug 19, 2026 Viel C, Shi Y, Trueman RP, Ruiz AJ, Rayner MLD

Nutrients

Alpha-Lipoic Acid, Vitamin D, Thiamine (B-1), Vitamin B6

Neuropathies, Homocysteine: Elevated, Hydrogen Peroxide Induced Toxicity

Neuroprotective Agents

View abstract

Research Abstracts Database

Abstracts Starting with "T"

Therapeutic effects of ginkgetin on rheumatoid arthritis: evidence from network pharmacology and experimental validation.

The Effect of Curcumin on Carbon Tetrachloride-Induced Lung Injury.

Therapeutic and prophylactic roles of oleuropein in experimental acute lung injury: Modulation of tumor necrosis factor-α and nuclear factor erythroid 2-related factor 2 pathways.

The Mechanism of Icariin in Regulating BMSCs for Treating Osteoporosis: A Review.

The Use of Curcumin to Target Oxidative Stress and Inflammation in Type 2 Diabetes Mellitus and Its Complications: Molecular Mechanisms and Therapeutic Perspectives.

The turmeric polyphenol calebin A relaxes rat aorta through Ca(V)1.2 channel inhibition with evidence for K(Ca)1.1 channel involvement.

Theaflavins counteract free fatty acid-driven oxidative-inflammatory injury in endothelial cells through Nrf2-NF-κB axis.

Tai Chi exercise improves sleep quality in older adults with mild insomnia by enhancing slow-wave activity during deep sleep: a 12-week randomized controlled trial.

Tai Chi Intervention Improves Hypertension by Reshaping the Neuro-Endocrine-Immune Network via the Acetylcholine-Cortisol-TNF-α Pathway.

The inhibition of deep peritoneal endometriosis by Andrographolide through macrophage M1 activity in an endometriosis mice model.

Therapeutic potential of nitric oxide and its donors in hemorrhagic and ischemic stroke: a systematic review.

The influence of in vitro gastrointestinal digestion on the Perilla frutescens leaf extract: Changes in the active compounds and bioactivities.

The mechanism of perilla oil in regulating lipid metabolism.

The Effects of Astaxanthin Supplementation on Exercise Recovery Biomarkers and Exercise Performance: A Systematic Review and Meta-Analysis.

The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial.

Topical Piperine for the Management of Burning Mouth Syndrome: A Case Series.

The Effect of Nigella sativa Supplementation on Cardiometabolic Health in Patients With Metabolic Diseases: A GRADE-Assessed Systematic Review and Meta-Analysis.

Thymoquinone combined with conventional antibiotics against pandrug-resistant Staphylococcus aureus: a pharmacodynamic and molecular simulation strategy to overcome bioavailability limitations.

Therapeutic evaluation of phytochemicals present in Nigella sativa seed oil for anxiolytic activity against the GABA-B receptor: a gas chromatography-mass spectrometry (GC-MS)-supported molecular dynamics-based in silico study.

Thymoquinone Enhances Tamoxifen Efficacy Against Triple-Negative Breast Cancer by Targeting EMT Signaling.

Thymoquinone enhances kidney function in obesity-induced renal impairment by targeting redox balance, inflammation, autophagy, and apoptosis.

Thymoquinone in Atherosclerosis: A Multi-Target Nutraceutical Modulating Inflammation, Oxidative Stress, and Lipid Metabolism.

Thymoquinone and caffeic acid phenethyl ester mitigate experimental ulcerative colitis: a biochemical and histopathological study.

The Effects of Neurotropic B Vitamins, Vitamin D3, and Alpha-Lipoic Acid in In Vitro Models of Neurodegeneration.