Western Diet

Name	AC	CK
Inflammation	6	27
Breast Cancer	7	22
Asthma	2	20
Obesity	10	18
Nonalcoholic fatty liver disease (NAFLD)	8	15
Colon Cancer	7	14
Colorectal Cancer	3	14
Metabolic Diseases	3	14
Attention Deficit Hyperactivity Disorder	2	12
Depression	2	12
Prostate Cancer	2	12
Prostate Cancer: Prevention	2	12
All-Cause Mortality	1	10
Allergies	1	10
Attention Deficit Disorder	1	10
Attention Deficit Disorder with Hyperactivity	1	10
Depressive Disorder	1	10
Esophageal Cancer	1	10
Fetal Origin of Adult Disease	1	10
High Fat Diet	5	10
Hypercholesterolemia	1	10
Infertility: Male	1	10
Insulin Resistance	5	10
Lipid Peroxidation	1	10
Prenatal Chemical Exposures	1	10
Sleep Disorders	1	10
Sperm Count: Low	1	10
Sperm Quality: Low	1	10
Stress	1	10
Suicidal Behavior	1	10
Tobacco Toxicity	1	10
Atherosclerosis	3	6
Diabetes Mellitus: Type 2	3	6
High Fructose Diet	3	6
Liver Cirrhosis	3	6
Breast Cancer: Prevention	2	4
Cancers: All	3	4
Cardiovascular Diseases	2	4
Endotoxemia	2	4
Liver Fibrosis	2	4
Metabolic Syndrome X	2	4
Osteoporosis	2	4
Oxidative Stress	2	4
Western-Style Diet Induced Toxicity	2	4
Gastrointestinal Inflammation	2	3
Acne	2	2
Aging	1	2
Anxiety Disorders	1	2
Bone Fractures	1	2
Brain Injury: Hippocampal Damage	1	2
Brain: Microglial Activation	1	2
Breast Cancer: Metastatic	1	2
Cardiac Hypertrophy	1	2
Cardiomyopathy	1	2
Chemically-Induced Liver Damage	1	2
Crohn's Disease	1	2
Diabetes Mellitus: Type 2: Prevention	1	2
Diabetic Complications	1	2
Dysbiosis	1	2
Endothelial Dysfunction	1	2
Escherichia coli Infections	1	2
Fatty Liver	1	2
Hepatic Steatosis	1	2
High Sugar Diet	1	2
Hip Fracture	1	2
Hyperglycemia	1	2
Infertility: Female	1	2
Intestinal Permeability	1	2
Lipopolysaccharide-Induced Toxicity	1	2
Liver Damage	1	2
Liver Disease	1	2
Memory Disorders	1	2
Neurodegenerative Diseases	1	2
Pancreatic Cancer	1	2
Sepsis	1	2
Sugar (Sucrose) Toxicity	1	2
Triglycerides: Elevated	1	2
Autoimmune Diseases	1	1
Chronic Kidney Disease (CKD)	1	1
Cognitive Decline/Dysfunction	1	1
Diabetes Mellitus: Type 1	1	1
Hyperinsulinism	1	1
Insulin: Elevated	1	1

Name	AC	CK	Focus
Inflammatory	1	2
Insulinotropic	1	1

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A pro-inflammatory diet was associated with a significantly higher risk of depression in a Mediterranean population.Sep 06, 2015

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Pubmed Data : Br J Nutr. 2015 Sep 7:1-9. Epub 2015 Sep 7. PMID: 26344165

Article Published Date : Sep 06, 2015

Study Type : Human Study

Additional Links

Diseases : Depression

Additional Keywords : Increased Risk

Anti Therapeutic Actions : Western Diet

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A Western diet increases breast cancer risk in postmenopausal Chinese women. Jul 01, 2007

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1443-8. Epub 2007 Jul 10. PMID: 17623805

Article Published Date : Jul 01, 2007

Study Type : Human Study

Additional Links

Diseases : Breast Cancer

Therapeutic Actions : Dietary Modification: Non-Western Diet, Dietary Modification: Vegetarian

Additional Keywords : Risk Reduction

Anti Therapeutic Actions : Western Diet

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A Western dietary pattern is prospectively associated with cardio-metabolic traits and incidence of the metabolic syndrome.Apr 30, 2018

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Pubmed Data : Br J Nutr. 2018 May ;119(10):1168-1176. PMID: 29759108

Article Published Date : Apr 30, 2018

Study Type : Human Study

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Public Health Nutr. 2016 Jun 24:1-8. Epub 2016 Jun 24. PMID: 27338763

Article Published Date : Jun 23, 2016

Study Type : Human Study

Additional Links

Diseases : All-Cause Mortality

Additional Keywords : Increased Risk

Anti Therapeutic Actions : Western Diet

Problem Substances : Sugar Sweetened Beverages

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Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer.Mar 25, 2018

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Pubmed Data : Eur J Nutr. 2018 Mar 26. Epub 2018 Mar 26. PMID: 29582162

Pubmed Data : Am J Physiol Heart Circ Physiol. 2018 Sep 28. Epub 2018 Sep 28. PMID: 30265151

Article Published Date : Sep 27, 2018

Study Type : Animal Study

Additional Links

Diseases : Endothelial Dysfunction

Anti Therapeutic Actions : Western Diet

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A western-style diet increases liver inflammation in mice with experimentally-induced sepsis.Jan 01, 2010

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Pubmed Data : Carcinogenesis. 1997 May;18(5):995-9. PMID: 9163686

Article Published Date : May 01, 1997

Study Type : Animal Study

Additional Links

Diseases : Prostate Cancer, Prostate Cancer: Prevention

Anti Therapeutic Actions : Western Diet

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A Western-style diet produces hyperproliferation of epithelial cells in several organs and that the changes can be prevented by increasing dietary calcium and vitamin D alone.Jan 20, 1999

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Pubmed Data : J Natl Cancer Inst. 1999 Jan 20;91(2):176-81. PMID: 9923860

Article Published Date : Jan 20, 1999

Study Type : Animal Study

Additional Links

Substances : Calcium, Vitamin D

Diseases : Cancers: All

Pharmacological Actions : Antiproliferative

Anti Therapeutic Actions : Western Diet

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A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development.Sep 01, 2003

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Pubmed Data : Br J Nutr. 2003 Sep;90(3):589-95. PMID: 13129465

Article Published Date : Sep 01, 2003

Study Type : Animal Study

Additional Links

Diseases : Osteoporosis

Anti Therapeutic Actions : Western Diet

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Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet.Jul 22, 2019

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Pubmed Data : Food Funct. 2019 Jul 23. Epub 2019 Jul 23. PMID: 31334539

Article Published Date : Jul 22, 2019

Study Type : Animal Study

Additional Links

Substances : Mango leaf

Diseases : Inflammation, Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, NF-kappaB Inhibitor

Anti Therapeutic Actions : Western Diet

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Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed mice.Jun 30, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ginseng Res. 2018 Jul ;42(3):352-355. Epub 2017 Apr 24. PMID: 29983617

Article Published Date : Jun 30, 2018

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Ginsenosides

Diseases : Cardiovascular Diseases, Diabetic Complications

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Plant Extracts

Anti Therapeutic Actions : Western Diet

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Antecedent intake of traditional Asian-style diets exacerbates pancreatic beta-cell function, growth and survival after Western-style diet feeding in weaning male rats.May 01, 2006

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Pubmed Data : J Nutr Biochem. 2006 May;17(5):307-18. Epub 2005 Aug 25. PMID: 16223578

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Diseases : Insulin Resistance

Anti Therapeutic Actions : Western Diet

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Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats.Apr 30, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharm Biol. 2013 May ;51(5):607-13. Epub 2013 Jan 31. PMID: 23363068

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2018 Nov 1 ;10(11). Epub 2018 Nov 1. PMID: 30388763

Article Published Date : Oct 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 Feb 18 ;6:21568. Epub 2016 Feb 18. PMID: 26888450

Article Published Date : Feb 17, 2016

Study Type : Animal Study

Additional Links

Diseases : Aging, Brain: Microglial Activation

Anti Therapeutic Actions : Western Diet

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Colon cancer prevention with walnuts.Dec 08, 2019

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Pubmed Data : Cancer Prev Res (Phila). 2019 Dec 9. Epub 2019 Dec 9. PMID: 31818852

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Nutr Food Res. 2020 Jun 11:e1900580. Epub 2020 Jun 11. PMID: 32526796

Article Published Date : Jun 10, 2020

Study Type : Animal Study

Additional Links

Substances : Fiber, Oat Bran, Rye

Diseases : Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Anti-Obesity Agents

Anti Therapeutic Actions : Western Diet

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Dietary flaxseed oil prevents western-type diet-induced non-alcoholic fatty liver disease.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Grape seed proanthocyanidin extract modulates the enteroendocrine system in models in which it also reduces food intake or body weight.Apr 11, 2019

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Pubmed Data : Mol Nutr Food Res. 2019 Apr 12:e1800912. Epub 2019 Apr 12. PMID: 30980498

Article Published Date : Apr 11, 2019

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

Anti Therapeutic Actions : Western Diet

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Grape-seed proanthocyanidins are able to reverse intestinal dysfunction and metabolic endotoxemia induced by a cafeteria diet.Apr 28, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Apr 29 ;11(5). Epub 2019 Apr 29. PMID: 31035432

Article Published Date : Apr 28, 2019

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Endotoxemia

Pharmacological Actions : Gastroprotective

Additional Keywords : Proanthocyanidins

Anti Therapeutic Actions : Western Diet

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High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer.Nov 30, 2016

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Pubmed Data : Nutr Res. 2016 Dec ;36(12):1325-1334. Epub 2016 Oct 20. PMID: 27866828

Article Published Date : Nov 30, 2016

Study Type : Animal Study

Additional Links

Diseases : Colon Cancer, High Fat Diet, Inflammation, Insulin Resistance, Obesity

Anti Therapeutic Actions : Western Diet

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Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pharmacol Exp Ther. 2018 May ;365(2):281-290. Epub 2018 Feb 22. PMID: 29472517

Article Published Date : Apr 30, 2018

Study Type : Animal Study

Additional Links

Substances : Nordihydroguaiaretic acid (NDGA)

Diseases : Metabolic Diseases

Pharmacological Actions : Antioxidants, MicroRNA modulator

Anti Therapeutic Actions : Western Diet

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Obesity induced by cafeteria diet disrupts fertility in the rat by affecting multiple ovarian targets.Aug 11, 2015

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Pubmed Data : Reprod Biomed Online. 2015 Aug 12. Epub 2015 Aug 12. PMID: 26380868

Article Published Date : Aug 11, 2015

Study Type : Animal Study

Additional Links

Diseases : Hyperglycemia, Infertility: Female, Obesity

Additional Keywords : Risk Factors

Anti Therapeutic Actions : Western Diet

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Oligonol may function to suppress MetS and the progression of geriatric diseases in western diet fed mice.Jun 30, 2016

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Pubmed Data : Anticancer Res. 2016 Jul ;36(7):3705-13. PMID: 27354644

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Lychee, Polyphenols

Diseases : Metabolic Syndrome X

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Hepatoprotective

Additional Keywords : Gene Expression Regulation, Plant Extracts

Anti Therapeutic Actions : Western Diet

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Preventive effect of spontaneous physical activity on the gut-adipose tissue in a mouse model that mimics Crohn's disease susceptibility.Jan 08, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cells. 2019 Jan 9 ;8(1). Epub 2019 Jan 9. PMID: 30634469

Article Published Date : Jan 08, 2019

Study Type : Animal Study

Additional Links

Diseases : Crohn's Disease

Therapeutic Actions : Exercise

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Physical Activity

Anti Therapeutic Actions : Western Diet

[+]

Propolis can attenuate DSS-induced colitis and provides new insight into diet-microbiota interactions during inflammatory bowel disease.Jan 13, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Hepatology. 2019 Jan 21. Epub 2019 Jan 21. PMID: 30664268

Article Published Date : Jan 20, 2019

Study Type : Animal Study

Additional Links

Diseases : Chemically-Induced Liver Damage

Anti Therapeutic Actions : Western Diet

Problem Substances : Electronic Cigarettes

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Pubmed Data : J Nutr. 2009 Nov;139(11):2072-8. Epub 2009 Sep 16. PMID: 19759248

Article Published Date : Nov 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Colon Cancer, Colorectal Cancer, Oxidative Stress

Anti Therapeutic Actions : Western Diet

[+]

Western-style diets induce tumorigenesis in the mouse colon. Nov 01, 1996

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Pubmed Data : Cancer Res. 1996 Nov 1;56(21):4910-6. PMID: 8895743

Article Published Date : Nov 01, 1996

Study Type : Animal Study

Additional Links

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

Anti Therapeutic Actions : Western Diet

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"Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization."Jan 01, 2011

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Pubmed Data : Nutr Metab (Lond). 2011 ;8:41. Epub 2011 Jun 24. PMID: 21699736

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Diseases : Acne, Cancers: All, Diabetes Mellitus: Type 1, Hyperinsulinism, Insulin: Elevated

Anti Therapeutic Actions : Western Diet

Problem Substances : Cow Milk, Insulin

Adverse Pharmacological Actions : Insulinotropic

[+]

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View the Evidence: 121 Abstracts with Western Diet Research

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A pro-inflammatory diet was associated with a significantly higher risk of depression in a Mediterranean population.Sep 06, 2015

A Western diet increases breast cancer risk in postmenopausal Chinese women. Jul 01, 2007

A Western dietary pattern is prospectively associated with cardio-metabolic traits and incidence of the metabolic syndrome.Apr 30, 2018

A western-style diet may lead to increased risks for prostate cancer, especially aggressive prostate cancer.May 01, 2008

ADHD Is Associated With a 'Western' Dietary Pattern in Adolescents.Jul 14, 2010

Consumption of a western pattern diet may be a risk factor for development of late age-related macular degeneration.Dec 05, 2019

Consumption of ultra-processed foods is strongly associated with frailty risk in older adults.May 31, 2019

Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals.Oct 31, 2019

Energy drink intake had detrimental effects related to stress, sleep dissatisfaction, mood, and suicidality in combination with junk food consumption.Oct 12, 2016

Environmental factors that are present before conception and up to the first 1000 days of life are associated with asthma.Nov 21, 2017

Fast food consumption was characterised by suppressed representation of lactobacilli and butyrate-producing bacteria.May 31, 2017

Fast food fed mice showed ocular pathology relevant to various stages of age-related macular degeneration including basal laminar deposits.Nov 16, 2019

Hass avocado modulates postprandial vascular reactivity and postprandial inflammatory responses to a hamburger meal in healthy volunteers.Nov 28, 2012

Incorporation of cashews into typical American diets could decrease total cholesterol and LDL cholesterol.Mar 28, 2017

Intake of fast-food items and sugar-sweetened drinks have a detrimental effect on future mortality risk.Jun 23, 2016

Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer.Mar 25, 2018

Maternal diet during pregnancy was independently associated with children's hyperactivity-inattention symptoms.Aug 31, 2018

The consumption of fast foods correlates to asthma in a dose-response pattern.Jul 03, 2018

The inclusion of nuts in a Western-style diet significantly improves the total sperm count and the vitality, motility, and morphology of the sperm. Oct 31, 2018

These results indicate that a proinflammatory diet is associated with increased risk of esophageal squamous cell carcinoma.Sep 22, 2015

These results suggest a pro-inflammatory diet is associated with adverse mental health.Sep 30, 2018

Walnuts improve semen quality in men consuming a Western-style diet. Jan 18, 2038

Western diet is associated with a smaller hippocampus.Sep 07, 2015

A cafeteria diet triggers intestinal inflammation and oxidative stress in obese rats.Jan 29, 2017

A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet.Apr 01, 2010

A Western diet induced hepatic inflammation, which was further enhanced by liquid fructose.Mar 14, 2017

A western diet is associated with perturbation of cholesterol homeostasis in middle aged rats, mostly in hippocampus.Jun 23, 2020

A western diet-induced endothelial dysfunction in female rats.Sep 27, 2018

A western-style diet increases liver inflammation in mice with experimentally-induced sepsis.Jan 01, 2010

A Western-style diet induced pancreatic epithelial cell hyperproliferation in mice, further suggesting that increased fat content and decreased calcium and vitamin D contribute to the development of pancreatic neoplasms.Nov 06, 1996

A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.Nov 01, 2001

A Western-style diet induces cardiac hypertrophy and fibrosis in an animal model.Oct 01, 2010

A Western-style diet induces hyperproliferation and hyperplasia in mouse mammary glands.Jan 01, 1996

A Western-style diet induces hyperproliferation in the epithelial cells of the mouse prostate.May 01, 1997

A Western-style diet produces hyperproliferation of epithelial cells in several organs and that the changes can be prevented by increasing dietary calcium and vitamin D alone.Jan 20, 1999

A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development.Sep 01, 2003

Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet.Jul 22, 2019

Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed mice.Jun 30, 2018

Antecedent intake of traditional Asian-style diets exacerbates pancreatic beta-cell function, growth and survival after Western-style diet feeding in weaning male rats.May 01, 2006

Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats.Apr 30, 2013

Aqueous extract of pomegranate enriched in ellagitannins prevents anxiety-like behavior.Nov 30, 2020

Bergamot has antioxidant effects against metabolic syndrome induced by a cafeteria diet. Mar 15, 2019

Bergamot polyphenols boost therapeutic effects of the diet on non-alcoholic steatohepatitis induced by junk food.Oct 31, 2018

Brain and behavioral perturbations in rats following western diet access.Apr 07, 2015

Calcium and vitamin D may prevent Western-style diet-induced colonic tumors. Jan 01, 2009

Chronic consumption of a western diet induces robust glial activation in aging mice.Feb 17, 2016

Colon cancer prevention with walnuts.Dec 08, 2019

Consumption of the total Western diet promotes colitis and inflammation-associated colorectal cancer in mice.Feb 19, 2020

Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice.May 29, 2018

Dietary fiber from oat and rye brans ameliorate western diet-induced body weight gain and hepatic inflammation.Jun 10, 2020

Dietary flaxseed oil prevents western-type diet-induced non-alcoholic fatty liver disease.Dec 31, 2016

Dietary supplementation of vitamin D prevents the development of western diet-induced metabolic, hepatic and cardiovascular abnormalities.Jul 31, 2018

Dietary supplementation with black raspberries appeared to ameliorate Western diet-enhanced colitis in mice.May 31, 2019

Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis.Sep 30, 2015

Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis.Dec 31, 2016

Effect of Myristica fragrans extract on total body composition in cafeteria diet induced obesity.Dec 31, 2018

Effects of passion fruit peel flour in cafeteria diet-induced metabolic disorders.Dec 18, 2019

Exercise prevents both the accumulation of senescent cells and the expression of the senescence-associated secretory phenotype.Mar 15, 2016

Galacto-oligosaccharides supplementation to Western-type diet improved body weight gain, dyslipidemia and insulin sensitivity.May 06, 2020

Galactooligosaccharide fiber supplementation improves intestinal barrier and significantly attenuates western-type diet-induced metabolic diseases.Oct 04, 2019

Ginger can have beneficial effects on health complications associated with unhealthy diet.Dec 31, 2018

Grape seed proanthocyanidin extract modulates the enteroendocrine system in models in which it also reduces food intake or body weight.Apr 11, 2019

Grape-seed proanthocyanidins are able to reverse intestinal dysfunction and metabolic endotoxemia induced by a cafeteria diet.Apr 28, 2019

Guarana supplementation attenuated obesity, insulin resistance, and adipokines dysregulation induced by a standardized human Western diet.Apr 30, 2019

Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet.Jan 12, 2020

Hesperidin and capsaicin prevent hepatic steatosis and other metabolic syndrome-related alterations in western diet-fed rats.Oct 09, 2018

High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer.Nov 30, 2016

Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet.Sep 30, 2018

Lycopene attenuates western-diet-induced cognitive deficits via improving glycolipid metabolism dysfunction and inflammatory responses in gut-liver-brain axis.Dec 31, 2018

Lycopene supplementation attenuates western diet-induced body weight gain.Jun 30, 2019

Maternal flavonoids intake reverts depression-like behaviour in rat female offspring.Mar 06, 2019

Maternal western style diet increases susceptibility to chemically-induced mammary carcinogenesis in female rats offspring.Dec 31, 2013

Western Diet

View the Evidence:
121 Abstracts with Western Diet Research