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Article Publish Status: FREE
Abstract Title:

Acute acalculous cholecystitis following COVID-19 vaccination: a case report.

Abstract Source:

Pan Afr Med J. 2022 ;41:291. Epub 2022 Apr 11. PMID: 35855047

Abstract Author(s):

Fabien Mukonki Kyungu, Aude Mukonki Katumba, Hermann Luhavo Kamwira, Aime Vonda Mayikuli, Adou Mala, Manix Ilunga Banza, Haladou Mahaman Manirou, Fiston Bolanda Tosali, Philippe Cilundika Mulenga

Article Affiliation:

Fabien Mukonki Kyungu

Abstract:

Acute acalculous cholecystitis is an acute inflammation of the gallbladder in the absence of stones, usually occurring in elderly and critically ill patients with underlying conditions. A 29-year-old man presented to the hospital complaining of abdominal pain in the right hypochondrium with permanent fever three days after Janssen COVID-19 vaccine inoculation. Abdominal ultrasound revealed a thickened gallbladder wall without evidence of gallstone consistent of an acute acalculous cholecystitis. Blood analyses revealed thrombocytopenia, eosinophilia and liver dysfunction. The Polymerase Chain Reaction (PCR) COVID-19 test was negative. As treatment, the patient benefited of pain management, antibiotic and fluid. In the evolution, there was a regression of clinical signs with persistence of liver dysfunction. The patient was discharged ten days after hospitalization. The Janssen COVID-19 vaccine is likely to induce acute acalculous cholecystitis as adverse event following vaccination.

Study Type : Human: Case Report

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