Abstract Title:

Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings.

Abstract Source:

Pediatr Radiol. 2010 Jul;40(7):1281-4. Epub 2010 Jan 30. PMID: 20119724

Abstract Author(s):

Hale Aydin, Esra Ozgul, Ahmet Muhtesem Agildere

Article Affiliation:

Department of Radiology, Baskent University Hospital, Ziya Gokalp, Cad 10, sok No: 45 Bahcelievler, Ankara 06610, Turkey. [email protected]


We present a previously healthy 6-month-old boy who was admitted to our hospital with lethargy, hypotonia and focal clonic seizures 6 days following diptheria, tetanus toxoid and whole-cell pertussis vaccination. A diagnosis of acute necrotising encephalopathy was made with the aid of MRI, including diffusion-weighted imaging and proton MR spectroscopy.

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