Abstract Title:

Acute pancreatitis associated with combined lisinopril and atorvastatin therapy.

Abstract Source:

Dig Dis. 2005 ;23(1):92-4. PMID: 15920330

Abstract Author(s):

Mehmet Kanbay, Haldun Sekuk, Ugur Yilmaz, Gürden Gur, Sedat Boyacioglu

Article Affiliation:

Department of Internal Medicine, Baskent University Faculty of Medicine, Fevzi Cakmak Caddesi, Bahcelievler, Ankara, Turkey. [email protected]


Few data exist about the incidence of drug-induced pancreatitis in the general population. Drugs are related to the etiology of pancreatitis in about 1.4-2% of cases. Although statins are generally well tolerated, acute pancreatitis has been reported in a few cases treated with atorvastatin, fluvastatin and simvastatin. A 86-year-old man with long-standing history of hypertension and hyperlipidemia, who was treated with lisinopril 10 mg and atorvastatin 20 mg once daily presented with acute pancreatitis. Other causes of the disease were ruled out. After cessation of the drugs, his physical condition improved and the amylase level decreased. To our knowledge, pancreatitis induced by a combination of atorvastatin together with lisinopril has never been reported in the literature.

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