Abstract Title:

A novel antifungal anthraquinone from seeds of Aegle marmelos Correa (family Rutaceae).

Abstract Source:

Fitoterapia. 2009 Aug 15. PMID: 19686813

Abstract Author(s):

Bhuwan B Mishra, Navneet Kishore, Vinod K Tiwari, Desh D Singh, Vyasji Tripathi


A new anthraquinone, 1-methyl-2-(3'-methyl-but-2'-enyloxy)-anthraquinone (1) has been isolated from seeds of Aegle marmelos Correa and was characterized on the basis of spectral analysis (UV, IR, (1)H NMR, (13)C NMR, 2D NMR and mass spectroscopy). The compound exhibited significant antifungal activity against pathogenic strains of Aspergillus species and Candida albicans in disc diffusion assay (MIC value of 6.25 mug/disc), microbroth dilution and percent


germination inhibition assays (MIC value of 31.25-62.5 mug/ml).


Study Type : Animal Study
Additional Links
Pharmacological Actions : Antifungal Agents : CK(494) : AC(306)

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