Agrimony contains compounds with blood sugar lowering activities. - GreenMedInfo Summary

OBJECTIVE: To isolate and identify the chemical constituents from the active section lowering blood sugar of agrimony. METHODS: The compounds were separated by repeated silica gel, Sephadex LH-20 and HPLC chromatographies. The structures of compounds isolated were identified by analysis of their spectral data and chemical properties. RESULTS: Nine compounds were isolated from the active section with lowering blood sugar of agrimony and their structures were identified as apigenin-7-O-3-D-glucopyranoside (1), catechin (2), quercetin (3), rutin (4), kaempferol-3-O-alpha-L-rhamnoside (5), Kampferol-3-O-beta-D-glucopyranoside (6), lutcolin-7-O-beta-D-glucopyranosidc (7), 19alpha, 24-dihydroxy ursolic acid (8), 3,3'-di-O-mcthyl ellagic acid4-O-beta-D-glucopyranoside (9). CONCLUSION: Compounds 1, 7, 8, 9 are isolated from thia plant for the first time.