Agrimony has acetylcholinesterase inhibitory properties. - GreenMedInfo Summary
Abstract Title:
Acetylcholinesterase inhibition by flavonoids from Agrimonia pilosa.
Abstract Source:
Molecules. 2007;12(9):2130-9. Epub 2007 Sep 3. PMID: 17962731
Abstract:
In a bioassay-guided search for acetylcholinesterase (AChE) inhibitors from 180 medicinal plants, an ethyl acetate extract of whole plants of Agrimonia pilosa ledeb yielded tiliroside (1), 3-methoxy quercetin (2), quercitrin (3) and quercetin (4). We report herein for the first time that all four flavonol compounds showed significant inhibitory effects on AChE, particularly quercetin (4), which showed twice the activity of dehydroevodiamine (DHED).
Article Published Date : Jan 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Agrimony : CK(18) : AC(13)
Pharmacological Actions : Acetylcholinesterase Inhibitor : CK(170) : AC(95)
