Antibacterial activity of silver nanoparticles: structural effects. - GreenMedInfo Summary
Antibacterial Activity of Silver Nanoparticles: Structural Effects.
Adv Healthc Mater. 2018 07 ;7(13):e1701503. Epub 2018 May 29. PMID: 29808627
The increase of antibiotic resistance in bacteria has become a major concern for successful diagnosis and treatment of infectious diseases. Over the past few decades, significant progress has been achieved on the development of nanotechnology-based medicines for combating multidrug resistance in microorganisms. Among this, silver nanoparticles (AgNPs) hold great promise in addressing this challenge due to their broad-spectrum and robust antimicrobial properties. This review illustrates the antibacterial mechanisms of silver nanoparticles and further elucidates how different structural factors including surface chemistry, size, and shape, impact their antibacterial activities, which are expected to promote the future development of more potent silver nanoparticle-based antibacterial agents.