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Abstract Title:

Antifungal Properties ofonspecies: A Systematic Review.

Abstract Source:

J Evid Based Integr Med. 2022 ;27:2515690X221132272. PMID: 36423242

Abstract Author(s):

Ali Malekzadeh Shafaroudi, Nadia Elyassi Gorji, Pegah Nasiri, Javad Javidnia, Mohammad Ebrahimi Saravi

Article Affiliation:

Ali Malekzadeh Shafaroudi

Abstract:

BACKGROUND AND PURPOSE: infections have increased significantly in the antimicrobial resistance era, and synthetic antifungal drugs have limitations. The present work aimed to review the antifungal properties of() as an herbal remedy.

METHOD: PubMed, Scopus, ScienceDirect, Web of Science, SID, Civilica, and Magiran databases were searched for the antifungal activity on,, dental biofilm, and clinical studies ofonspecies.

RESULTS: Overall, 33 articles evaluated the effect ofonspecies and classified them into four groups, as follows in vitro (23), dental biofilm (6), in vivo (2), and clinical studies (3). All studies consideredeffective in reducing or even inhibiting the growth ofspecies. NoMFC significant differences were seen in the effect ofon susceptiblecompared to the resistant groups ofin the studies. It was also influential in inhibitingand.

CONCLUSION: Considering the side effects and resistance of current antifungal drugs as well as the benefits of using herbal medicines, such as lower cost, less likely to develop drug resistance, the absence of side effects, and toxicity compared with chemical onesit is possible as a powerful alternative to replace or combine with the current antifungal forinfection therapy along with other therapies.

Study Type : Review

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