Antimicrobial diterpenoids of Wedelia trilobata. - GreenMedInfo Summary
Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc.
Molecules. 2016 Apr 7 ;21(4):457. Epub 2016 Apr 7. PMID: 27070557
Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1-7. Their structures and relative configuration were elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR experiments. The antimicrobial activities of all isolated diterpenoids were evaluated against a panel of bacteria and fungi.