Article Publish Status: FREE
Abstract Title:

Antimicrobial Effect of Natural Berry Juices on Common Oral Pathogenic Bacteria.

Abstract Source:

Antibiotics (Basel). 2020 Aug 24 ;9(9). Epub 2020 Aug 24. PMID: 32847029

Abstract Author(s):

Stefan Kranz, André Guellmar, Philipp Olschowsky, Silke Tonndorf-Martini, Markus Heyder, Wolfgang Pfister, Markus Reise, Bernd Sigusch

Article Affiliation:

Stefan Kranz


(1) Background: Antimicrobial agents such as chlorhexidine (CHX) are commonly used in oral plaque control. However, sometimes those agents lack antimicrobial efficiency or cause undesired side effects. To identify alternative anti-infective agents, the present study investigated the antibacterial activity of all-fruit juices derived from blackcurrant, redcurrant, cranberry and raspberry on common oral pathogenic gram-positive and gram-negative bacteria (,,,,,,,). (2) Methods: Antibacterial efficiency was evaluated by agar diffusion assay and in direct contact with bacteria in planktonic culture. Furthermore, cytotoxicity on human gingival fibroblasts was determined. (3) Results: Blackcurrant juice was most efficient at suppressing bacteria; followed by the activity of redcurrant and cranberry juice. Raspberry juice only suppressedsignificantly. Only high-concentrated blackcurrant juice showed minimal cytotoxic effects which were significantly less compared to the action of CHX. (4) Conclusion: Extracts from natural berry juices might be used for safe and efficient suppression of oral pathogenic bacterial species.

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