Abstract Title:

Synthesis of Mannich bases of antineoplaston A10 and their antitumor activity.

Abstract Source:

Arch Pharm Res. 1994 Dec ;17(6):467-9. PMID: 10319160

Abstract Author(s):

B G Choi, H K Seo, B H Chung, S U Choi, C O Lee

Article Affiliation:

College of Pharmacy, Chonnam National University, Kwangju, Korea.


Some Mannich bases of Antineoplaston A10 which is antitumor agent under clinical investigation were synthesized and tested for cytotoxicity. The tested compounds (2a, 2b, 2d) showed good activity comparable to that of carboplatin.

Study Type : Review

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