Abstract Title:

Antiradical, antimicrobial and cytotoxic activities of commercial beetroot pomace.

Abstract Source:

Food Funct. 2013 Feb 19. Epub 2013 Feb 19. PMID: 23423147

Abstract Author(s):

Jelena J Vulić, Tatjana N Cebović, Vladimir M Canadanović, Gordana S Cetković, Sonja M Djilas, Jasna M Canadanović-Brunet, Aleksandra S Velićanski, Dragoljub D Cvetković, Vesna T Tumbas

Article Affiliation:

Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, Novi Sad, Serbia. [email protected]


The by-product of food processing is often utilized as feed, and for the preparation of dietary fiber and biofuel. However, these products are also promising sources of bioactive antioxidants and color giving compounds, which could be used as additives in the food, pharmaceutical and cosmetic industry. The aim of this study was to investigate the phytochemical profile, and the antiradical, antimicrobial and cytotoxic activities of industrial beetroot pomace extract (BPE). The content of phenolics (45.68 mg gallic acid equivalents g(-1)), flavonoids (25.89 mg rutin equivalents g(-1)) and betalains (4.09 mg betanin g(-1); 7.32 mg vulgaxanthin I g(-1)) were determined spectrophotometrically. The antiradical activity on DPPH (EC(50)(DPPH)˙ = 0.0797 mg ml(-1)), hydroxyl (EC(50)˙(OH) = 0.0655 mg ml(-1)) and stress. The largest decreases in EAC cell numbers were observed in the pre-treated male (approximately 53%) and female (approximately 47%) mice, and also the EAC cell superoxide anion (EC(50)(O2)˙(-) = 1.0625 mg ml(-1)) radicals were measured by electron spin resonance (ESR) spectroscopy. The antimicrobial activity was determined using the agar-well diffusion method. Gram(-) bacteria (Salmonella typhimurium, Citrobacter freundii) and Gram(+) bacteria, (Staphylococcus aureus, Staphylococcus sciuri, Bacillus cereus) showed high susceptibility, while yeasts and moulds were resistant. BPE exhibits cytotoxic properties against Ehrlich carcinoma (EAC) cells in vivo due to induction of oxidative viability was decreased after administration of BPE. The activities of the antioxidant enzymes, xanthine oxidase (XOD) and peroxidase (Px), were significantly different between the untreated EAC control group and all other groups that were treated with BPE. The XOD and Px activities were very low in untreated malignant cells, but increased significantly after administration of BPE. Our results show that BPE holds promise in the food industry as a source of bioactive compounds.

Study Type : Review

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.