Abstract Title:

Antitumour activities of sesquiterpene lactones from Inula helenium and Inula japonica.

Abstract Source:

Z Naturforsch C J Biosci. 2012 Jul-Aug;67(7-8):375-80. PMID: 23016276

Abstract Author(s):

Yong Li, Zhi-Yu Ni, Meng-Chu Zhu, Mei Dong, Si-Ming Wang, Qing-Wen Shi, Man-Li Zhang, Yu-Fang Wang, Chang-Hong Huo, Hiromasa Kiyota, Bin Cong

Article Affiliation:

Yong Li


Eight sesquiterpene lactones were isolated from the roots of Inula helenium and flowers of I. japonica. Among them, isoalantolactone (3) and santamarine (6) exhibited significant growth inhibitory activities against gynecologic cancer cell lines, while others weakly inhibited the growth of the cell lines (IC50

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032)

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