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Article Publish Status: FREE
Abstract Title:

Clinical Effects of the Extract of the Seeds of the Indian Celery--In Horses Affected by Chronic Osteoarthritis.

Abstract Source:

Animals (Basel). 2019 Aug 20 ;9(8). Epub 2019 Aug 20. PMID: 31434330

Abstract Author(s):

Beatrice Battaglia, Mario Angelone, Elena Vera, Giuseppina Basini, Simona Bussolati, Massimiliano Paci, Maurizio Del Bue, Raffaella Aldigeri, Stefano Grolli, Fausto Quintavalla, Roberto Ramoni

Article Affiliation:

Beatrice Battaglia

Abstract:

The extract of the seeds from Indian celery,(CSE), tested in experimental animals (rodents), and in humans affected by chronic osteoarthritic diseases, exhibits anti-inflammatory effects that can be compared, to some degree, to those of non-steroid anti-inflammatory drugs (NSAID). In view of a potential use of CSE in the equine species, it was tested on horses affected by chronic articular pathologies. The trial was performed on 20 horses divided into three different groups, orally treated with 0 (controls), 7.0 or 30 g of CSE BID. Basic orthopedic examinations were conducted, vital signs were observed, and blood samples collected. Improvement was observed at the highest dosage tested (30 g of CSE BID), as reflected in the score values of three clinical parameters, (i) amplitude and (ii) sensitivity to passive flexion and (iii) flexion test. Since the improvement of these parameters can be correlated with a lower perception of the pain, the present data suggest that the CSE treatment can have an analgesic effect in horses affected by chronic osteoarthritic diseases.

Study Type : Animal Study
Additional Links
Pharmacological Actions : Analgesics : CK(2569) : AC(470)

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