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Article Publish Status: FREE
Abstract Title:

Investigating the effectiveness of theL. (fenugreek) seeds in mild asthma: a randomized controlled trial.

Abstract Source:

Allergy Asthma Clin Immunol. 2018 ;14:19. Epub 2018 May 2. PMID: 29743896

Abstract Author(s):

Majid Emtiazy, Laleh Oveidzadeh, Minoo Habibi, Leila Molaeipour, Daryush Talei, Zahra Jafari, Mahmoud Parvin, Mohammad Kamalinejad

Article Affiliation:

Majid Emtiazy

Abstract:

Background: Asthma is one of the important chronic diseases. The asthma prevalence is increasing in last decades. Despite the presence of good controller drugs like corticosteroids, about 60% of asthmatic patients use alternative medicine. This study was done to determine the effectiveness of(fenugreek) seeds in mild asthma.

Methods: It is a double blind trial with placebo effect. One of the ancient prescriptions from Persian Medicine was selected. The participants were divided to three groups randomly. On group received fenugreek syrup one received honey syrup and the third received placebo. Duration of treatment was 4 weeks. Quality of life, Lung function tests and IL-4 levels were evaluated before and after treatment.

Results: From 90 participants to study 79 completed the process. After study there was significant increase in quality of the life and lung function tests and IL-4 levels in fenugreek and honey groups.

Conclusion: FEV1 level was improved more than 10% in fenugreek group. Treatment was well tolerated. No serious side effects were reported during the study. The aqueous extract of fenugreek seeds appears to be effective and safe in treatment of mild asthma.The study was recorded with the Iranian Registry of Clinical trials [https://www.irci.ir], registration code: IRCT2016011325991N1.

Study Type : Human Study

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Sayer Ji
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