Ashwaganda protects the cartilage matrix in osteoarthritis. - GreenMedInfo Summary

Abstract Title:

Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis.

Abstract Source:

Blood Coagul Fibrinolysis. 2008 Dec;19(8):785-92. PMID: 17435322

Abstract Author(s):

Venil N Sumantran, Asavari Kulkarni, Sanjay Boddul, Trushna Chinchwade, Soumya J Koppikar, Abhay Harsulkar, Bhushan Patwardhan, Arvind Chopra, Ulhas V Wagh

Abstract:

This is the first report describing two novel chondroprotective activities of aqueous extracts of Withania somnifera root powder.First,these extracts had a statistically significant,short-term chondroprotective effect on damaged human osteoarthritic cartilage matrix in 50% of the patients tested. Second,these extracts caused a significant and reproducible inhibition of the gelatinase activity of collagenase type 2 enzyme in vitro.

Article Published Date : Dec 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(418) : AC(268)
Diseases : Osteoarthritis : CK(1449) : AC(546)

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Key Research Topics

Substance

Ashwagandha

Disease

Osteoarthritis

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