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Abstract Title:

Association between nut consumption and cancer risk: a meta-analysis.

Abstract Source:

Nutr Cancer. 2022 Aug 3:1-13. Epub 2022 Aug 3. PMID: 35920657

Abstract Author(s):

Chang Cao, Xinyan Gan, Yan He, Shiqi Nong, Yonglin Su, Zheran Liu, Yu Zhang, Xiaolin Hu, Xingchen Peng

Article Affiliation:

Chang Cao

Abstract:

This study aims to conduct a meta-analysis and dose-response analysis of the relationship between nut intake and cancer risk and mortality. Electronic databases were searched. A meta-analysis was conducted to calculate the pooled effect sizes (ESs) with the corresponding 95% CIs, and a dose-response analysis was performed. A random-effects model was used in the statistical analysis. Two independent reviewers completed the full-text screening, data extraction, and quality assessment. We included 17 articles in the present meta-analysis. Total nuts intake was revealed to be significantly associated with reduced cancer risk (ES: 0.9; 95% CI: 0.86-0.95; < 0.001) and cancer mortality (ES: 0.88; 95% CI: 0.85-0.92, < 0.001), especially lung cancer risk (ES: 0.86; 95% CI: 0.81-0.91, < 0.001) and gastric cancer risk (ES: 0.79; 95% CI: 0.68-0.91, = 0.001). Moreover, a 10 g/d increment of tree nuts consumption was associated with a 20% cancer mortality reduction (ES: 0.80; 95% CI: 0.71-0.89; < 0.0001). Nuts intake is significantly associated with the reduction of cancer risk and mortality. Especially, nuts intake is significantly associated with reduced lung cancer risk and gastric cancer risk. Noticeably, a 10 g/d increase in tree nuts intake is related to a 20% reduction in overall cancer mortality.

Study Type : Meta Analysis

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