Abstract Title:

Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction.

Abstract Source:

Am J Cardiol. 2004 Nov 15 ;94(10):1306-10. PMID: 15541254

Abstract Author(s):

Marc A Silver, Peter H Langsjoen, Szabolcs Szabo, Harish Patil, Allan Zelinger

Article Affiliation:

Heart Failure Institute, Department of Medicine, Advocate Christ Medical Center, University of Illinois/Christ Cardiovascular Disease Fellowship Program, Oak Lawn, Illinois 60453, USA. [email protected]


This study evaluated left ventricular diastolic function with Doppler echocardiography before and after statin therapy. Statin therapy worsened diastolic parameters in most patients; coenzyme Q(10) supplementation in patients with worsening diastolic function with statin therapy improved parameters of diastolic function.

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