Autoimmune hepatitis associated with atorvastatin use has been reported. - GreenMedInfo Summary
Abstract Title:
Autoimmune hepatitis revealed by atorvastatin.
Abstract Source:
Eur J Gastroenterol Hepatol. 2003 Aug ;15(8):921-4. PMID: 12867804
Article Affiliation:
Department of Internal Medicine, Clinical Immunology Unit, University of Genoa, Genoa, Italy.
Abstract:
Cases of acute hepatitis induced by statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) have been reported. A 65-year-old woman was admitted to our hospital because of fatigue, jaundice and altered liver function tests while on treatment with atorvastatin. On the basis of clinical, serological and histological findings, a score leading to a diagnosis of autoimmune hepatitis was reached. We suggest that atorvastatin may have revealed an underlying autoimmune hepatitis.
Article Published Date : Aug 01, 2003
Study Type : Human Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(1157) : AC(504), Hepatitis: Autoimmune : CK(43) : AC(9), Statin-Induced Pathologies : CK(1638) : AC(327)
Problem Substances : Atorvastatin : CK(516) : AC(99), Statin Drugs : CK(4369) : AC(517)
Adverse Pharmacological Actions : Hepatotoxic : CK(335) : AC(96)
