Article Publish Status: FREE
Abstract Title:

Autoimmune hepatitis following influenza virus vaccination: Two case reports.

Abstract Source:

Medicine (Baltimore). 2018 Jul ;97(30):e11621. PMID: 30045302

Abstract Author(s):

Tokio Sasaki, Yuji Suzuki, Kazuyuki Ishida, Keisuke Kakisaka, Hiroaki Abe, Tamotsu Sugai, Yasuhiro Takikawa

Article Affiliation:

Tokio Sasaki


RATIONALE: Although immunization could possibly cause autoimmune hepatitis (AIH), to date, no cases of AIH have been reported secondary to influenza virus vaccination. This paper describes 2 women who developed AIH after receiving influenza virus vaccination.

PATIENT CONCERNS AND DIAGNOSES: Two women presented with elevation of liver enzymes after receiving influenza virus vaccination. Both patients were diagnosed with AIH using the International Autoimmune Hepatitis Group criteria.

INTERVENTION AND OUTCOMES: Both patients were treated with prednisolone. After the initiation of prednisolone, serum aminotransferase levels were observed to return to the reference range in both patients.

LESSONS: Influenza virus vaccination could trigger the development of AIH. Clinicians should be mindful of the fact that AIH can occur after influenza virus vaccination.

Study Type : Human: Case Report

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Sayer Ji
Founder of GreenMedInfo.com

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