Abstract Title:

Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry).

Abstract Source:

Phytother Res. 2008 Jul;22(7):979-81 PMID: 18389483

Abstract Author(s):

Hideyuki Tomosaka, Young-Won Chin, Angela A Salim, William J Keller, Heebyung Chai, A Douglas Kinghorn


Full Citation: "Activity-guided fractionation of an EtOAc-soluble partition of the MeOH extract from the root bark of Berberis vulgaris L. (barberry), using a hydroxyl radical-scavenging assay, led to the isolation and identification of three phenolic compounds of a previously known structure, N-(p-trans-coumaroyl)tyramine, cannabisin G and (+/-)-lyoniresinol. Of these, cannabisin G and (+/-)-lyoniresinol exhibited antioxidant activity in this bioassay. Furthermore, it was found that cannabisin G showed cytoprotective activity in cultured MCF-7 cells modulated by hydrogen peroxide."

Study Type : In Vitro Study
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